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- 详细信息
- 技术资料
- 保存条件:
RT
- 保质期:
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -318℃ for several months.
- 英文名:
Clofarabine
- 库存:
详询
- 供应商:
详询
- CAS号:
123318-82-1
- 规格:
2mg/10mg/50mg/100mg/1ml/10mM
| 规格: | 2mg | 产品价格: | ¥298.0 |
|---|---|---|---|
| 规格: | 10mg | 产品价格: | ¥472.75 |
| 规格: | 50mg | 产品价格: | ¥998.0 |
| 规格: | 100mg | 产品价格: | ¥1747.0 |
| 规格: | 1ml/10mM | 产品价格: | ¥318.0 |
ID:T0297
PURITY:0.99
Formula:C10H11ClFN5O3
MolWt:303.6823
Appearance:白色粉末
Solubility:G4Soluble in DMSO > 10 mM
Bioactivity:Clofarabine is a purine nucleoside antimetabolite that is being studied in the treatment of cancer. It is marketed in the U.S. and Canada as Clolar. In Europe and Australia/New Zealand the product is marketed under the name Evoltra. Clofarabine is used in paediatrics to treat a type of leukaemia called relapsed or refractory acute lymphoblastic leukaemia (ALL), only after at least two other types of treatment have failed. It is not known if the drug extends life expectancy. Some investigations of effectiveness in cases of acute myeloid leukaemia (AML) and juvenile myelomonocytic leukaemia (JMML) have been carried out.
Status:USP
Pathways:DNA Damage/DNA Repair
Target:RNA Synthesis
Receptor:Ribonucleotide reductase
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