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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
-20°C
- 保质期:
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -214℃ for several months.
- 英文名:
Pemetrexed disodium
- 库存:
详询
- 供应商:
详询
- CAS号:
150399-23-8
- 规格:
2mg/10mg/50mg/100mg/1ml/10mM
| 规格: | 2mg | 产品价格: | ¥368.0 |
|---|---|---|---|
| 规格: | 10mg | 产品价格: | ¥779.5 |
| 规格: | 50mg | 产品价格: | ¥2315.5 |
| 规格: | 100mg | 产品价格: | ¥3972.5 |
| 规格: | 1ml/10mM | 产品价格: | ¥685.0 |
ID:T0189L
PURITY:0.97
Formula:C20H19N5Na2O6
MolWt:471.37
Appearance:白色结晶
Solubility:G4Water 94 mg/mL;DMSO <1 mg/mL
Bioactivity:Pemetrexed (brand name Alimta) is a chemotherapy drug manufactured and marketed by Eli Lilly and Company. Its indications are the treatment of pleural mesothelioma as well as non-small cell lung cancer.
Status:
Pathways:Metabolism;Enzyme
Target:DHFR inhibitor
Receptor:TS, DHFR,GARFT and AICARFT;DHFR;TS
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文献和实验Structural Determinants of Folate and Antifolate Membrane Transport by the Reduced Folate Carrier
of antifolates typified by Tomudex and Pemetrexed. Further, impaired cellular uptake of antifolates is a frequent mode of drug resistance. The ubiquitously expressed transporter termed the reduced folate carrier (RFC) is the best characterized of the folate
33 g disodium EDTA 9.3 g 5.58 (The TBE should be fresh-if the boric acid precipitates, make a fresh stock--we find that a 6x solution lasts longer before precipitating
常用化学试剂分子量 Molecular Weights of Commonly Used Chemicals
Ammonium Sulfate 132.14 Polyvinylpyrrolidone 40,000 Ampicillin 371.4 Potassium Acetate 98.14 ATP, disodium salt 605.19
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