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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Polypeptide
- 形态:
液体
- 保存条件:
-20度
- 克隆性:
多克隆
- 标记物:
无
- 适应物种:
human
- 宿主:
兔
- 应用范围:
wb
- 浓度:
0.1ml
- 靶点:
DLL3 Antibody
- 抗体英文名:
DLL3 Antibody
- 抗体名:
DLL3 Antibody
- 规格:
0.1ml/0.2ml
基因名 DLL3
基因全名 Delta-like protein 3
Tissue Specificity Inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). .
Sequence Similarities Delta-like protein 3;Drosophila Delta homolog 3;Delta3;DLL3;
Uniprot ID DLL3: Q9NYJ7
产品名称 DLL3 Antibody
产品描述 Anti-DLL3 Antibody validated for WB in Human.
文献引用格式 DLL3 Antibody
应用范围 WB
抗体来源 Rabbit
免疫原 Polypeptide
This gene encodes a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Mutations in this gene cause autosomal recessive spondylocostal dysostosis 1. Two transcript variants encoding distinct isoforms have been identified for this gene.
基因全名 Delta-like protein 3
Tissue Specificity Inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). .
Sequence Similarities Delta-like protein 3;Drosophila Delta homolog 3;Delta3;DLL3;
Uniprot ID DLL3: Q9NYJ7
产品名称 DLL3 Antibody
产品描述 Anti-DLL3 Antibody validated for WB in Human.
文献引用格式 DLL3 Antibody
应用范围 WB
抗体来源 Rabbit
免疫原 Polypeptide
This gene encodes a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Mutations in this gene cause autosomal recessive spondylocostal dysostosis 1. Two transcript variants encoding distinct isoforms have been identified for this gene.
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文献和实验相关实验
外。配体蛋白结合到胞外域后诱导蛋白切断并释放胞内域,胞内域进而进入细胞膜并调控基因表达。Notch 信号通路提升了神经增殖过程中的增殖信号,而其活性被 Numb 所抑制,以促进神经分化。他在胚胎发育中起到重要的调控作用。8. Hedgehog signaling pathwayHedgehog 通路调控机制:Hh 信号传递受靶细胞膜上两种受体 Patched (Ptc) 和 Smoothened (Smo) 的控制。受体 Ptc 由肿瘤抑制基因 Patched 编码,是由 12 个跨膜区的单一肽链构成
Notch信号途径调控。调控发生在不同水平,包括Notch-配体互作、受体和配体的运输、泛素化降解等。 在白血病转化中Notch潜在的信号通路
重要的Notch信号途径涉及Notch的三步蛋白质水解活化。许多相关分子 和体内生化过程参与Notch信号途径调控。调控发生在不同水平,包括Notch-配体互作、受体和配体的运输、泛素化降解等。 在白血病转化中Notch潜在的信号通路
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DLL3 Notch信号通路Delta样配体3抗体
¥660




