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文献和实验Antisense methodologies have been used extensively to inhibit the expression of specific genes with a view to elucidating their role in particular cellular processes ( 1 ). The technique is based on the ability of mRNA to bind
Generation of Functional Multipotent Keratinocytes from Mouse Induced Pluripotent Stem Cells
and efficiency of keratinocyte derivation depending on the mouse genetic background used in the study. Both protocols employ applications of retinoic acid and bone-morphogenetic protein-4 and growth on collagen type IV-coated dishes to induce iPSC differentiation
Mouse Models of Autoimmune Blistering Diseases Induced by the Passive Transfer of Antibodies
transmembrane protein. A single intraperitoneal injection of human or rabbit IgG against pathogenic epitopes for COL17 can induce skin fragility in neonatal mice that express human COL17. Since amino acid sequences of the pathogenic epitopes for COL17
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