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- 文献和实验
- 技术资料
- 抗体名:
STRO-1 Antibody (APC) 抗体
- 抗体英文名:
STRO-1 Antibody (APC)
- 靶点:
STRO-1
- 浓度:
0.1 mg/ml
- 应用范围:
FC
- 适应物种:
Human, Rabbit, Rat
- 保质期:
12 months from date of receipt.
- 抗原来源:
详询
- 目录编号:
orb179924
- 级别:
科研
- 库存:
99
- 供应商:
Biorbyt
- 标记物:
APC
- 克隆性:
Monoclonal
- 保存条件:
详询
- 亚型:
Mouse IgM lambda
- 免疫原:
详询
- 规格:
0.1 mg
产品子类型: Primary Antibody
描述: Mouse monoclonal antibody conjugated to APC which recognizes STRO-1.
克隆号: STRO-1
别名: HSC70, HSPA8, LAP1, HSC54, NIP71, HEL-33, HEL-S-72p
应用说明: Flow cytometry: Recommended dilution: 1-5 μg/ml.
免疫原: Human CD34 positive bone marrow cells
防腐剂: Stabilizing Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
纯化方法: Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
特异性: The mouse monoclonal antibody STRO-1 recognizes an extracellular epitope of the cell surface antigen STRO-1 expressed by bone marrow mesenchymal stromal cells and nucleated erythroid precursors, but not by committed hematopoietic progenitors.
UniProt ID: P11142
Entrez 基因 ID: 3312
保存条件: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
备注: For research use only.

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文献和实验A Method to Isolate and Purify Human Bone Marrow Stromal Stem Cells
The STRO-1 antibody can be used as a single reagent to isolate human bone marrow stromal stem cells (BMSSC), owing to its restricted specificity to a cell surface molecule expressed by clonogenic BMSSC, with little or no reactivity
抗体的概念 抗体(antibody, Ab),也叫免疫球蛋白(immunoglobulin, Ig),是血液和组织液中的一类糖蛋白,由B细胞接受抗原刺激后增殖分化成的浆细胞产生,能与相应抗原特异性地结合,是介导体液免疫的重要效应分子。1968年和1972年世界卫生组织和国际免疫学联合会的专门委员会先后决定,将具有抗体活性或化学结构与抗体相似的球蛋白统称为免疫球蛋白。后来研究证实,Ig和Ab在结构及功能上完全一致,因此可认为二者的概念等同。Ig可分为分泌型和跨模型,前者主要存在于血液和组织液中
A Method to Isolate, Purify, and Characterize Human Periodontal Ligament Stem Cells
on the expression of MSC-associated surface markers STRO-1 antigen, CD146 (MUC-18), CD29 (integrin β-1), CD44, and CD106 (VCAM-1). Although no single antibody demonstrates specificity for MSCs, isolation based on the expression of individual markers results
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