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文献和实验v468.chapter 1 经典 Wnt/b-Catenin 信号通路 (英文完整版)
represstarget genes by recruiting transcriptional co-repressors (Groucho/TLE) to their promoters and/or enhancers. B Wnt on : interaction of a Wnt ligand with its specific receptor complex containing a Frizzled family member and low-density lipidreceptor (LRP)-5
v468. chapter 4 WNT 细胞通路 检测细胞GSK3活性与表达水平
has been demonstrated for Drosophila Wingless (12) ,Xenopus Wnt8 (17) , and mammalian Wnt1 (10) . We haveused mammalian Wnt3a in our studies. 4. Many commercial antibodies that recognise phosphorylatedand non-phosphorylated epitopes on GSK3 are listed in Table
was unresponsive to the transcription factors (Fig. 4D). The sequence 5'-GGAA-3' (ETS-binding site-2, EBS2) is conserved between mouse and the human promoters, and in the mouse it interacts with the ETS-1 protein, a transcription factor of the ETS family expressed
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