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文献和实验The TNF superfamily member TWEAK has emerged as a pleiotropic cytokine that regulates many cellular functions that include immune/inflammatory activity, angiogenesis, cell proliferation, and fate. TWEAK through its inducible receptor, FGF
Induction of Tumor Cell Apoptosis by TRAIL Gene Therapy
Members of the tumor necrosis factor (TNF) superfamily influence a variety of immunological functions, including cellular activation, proliferation, and death, upon interaction with a corresponding superfamily of receptors
Among cytokine families, the tumor necrosis factor (TNF) superfamily stands out as the one that contains several members with cytotoxic activity (1 –3 ). The best characterized is the prototypic member TNF-α, which is cytotoxic to a range
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