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文献和实验ErbB Membrane Tyrosine Kinase Receptors: Analyzing Migration in a Highly Complex Signaling System
The erbB membrane tyrosine kinases (EGF receptor, erbB2, erbB3, and erbB4) are a family of structurally similar transmembrane proteins that act as receptors for the EGF and neuregulin (NRG) families of growth factors. ErbB
Tyrosine Kinase Inhibitors Against EGF Receptor-Positive Malignancies
epidermal growth factor receptor (EGFR) (1 –6 ), Janus kinases (JAKs) (7 –13 ), Bruton’s tyrosine kinase (BTK) (14 –16 ), platelet-derived growth factor (PDGF) (17 ), protein kinase C (PKC) (18 –24 ), Lck (25 , 26 ), Trk (27 –30
Immunohistochemical Determination of EGFR-Tyrosine Kinase Inhibition in Clinical Samples
The epidermal growth factor receptor (EGFR) family consists of four closely related transmembrane receptors including the EGFR (erbB1), erbB2 (HER2), erbB3 (HER3), and erbB4 (HER4). EGFR (erbB1) was the first member to be described
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