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Pluripotency Maintenance Pathway: Receptors: IL6ST (GP130), LIFR.
Transcription Factor: STAT3.
Fibroblast Growth Factor (FGF) Signaling Pathway: Receptors: FGFR1, FGFR2, FGFR3, FGFR4. Transcription Factor: CDX2.
Hedgehog Signaling Pathway: Receptors & Co-Receptors: PTCH1, PTCHD2, SMO.
Transcription Factors & Co-Factors: GLI1, GLI2, GLI3, SUFU.
Notch Signaling Pathway: Receptors & Co-Receptors: NCSTN, NOTCH1, NOTCH2, NOTCH3, NOTCH4, PSENEN, PSEN1, PSEN2.
Transcription Factor: RBPJL.
TGFβ Superfamily Signaling Pathway: Receptors & Co-Receptors: ACVRL1, ACVR1, ACVR1B, ACVR1C, ACVR2A, ACVR2B, AMHR2, BMPR1A, BMPR1B, BMPR2, ENG, LTBP1, LTBP2, LTBP3, LTBP4, RGMA, TGFBR1, TGFBR2, TGFBR3, TGFBRAP1.
Transcription Factors & Co-Factors: EP300, SMAD1, SMAD2, SMAD3, SMAD4, SMAD5, SMAD6, SMAD7, SMAD9, CREBBP, E2F5, RBL1, RBL2, SP1, ZEB2.
Wnt Signaling Pathway: Receptors: FZD1, FZD2, FZD3, FZD4, FZD5, FZD6, FZD7, FZD8, FZD9, LRP5, LRP6, VANGL2.
Transcription Factors & Co-Factors: BCL9, BCL9L, CTNNB1, LEF1, NFAT5, NFATC1, NFATC2, NFATC3, NFATC4, PYGO2, TCF7L1, TCF7L2, TCF7.
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文献和实验简介：什么是PCR芯片？ 实时定量PCR是检测基因表达最灵敏，最可靠的方法。通过在试验过程中，实时监测荧光染料的信号变化，反映样品中的基因拷贝数。实时定量PCR线性范围广（能达到5个数量级），因此可以检测同一样品中表达量极低的基因和表达量很高的基因。但是，由于实时定量PCR需要制备标准曲线和同时分析内参基因，因此，每次实验只能检测少数几个基因的表达水平，若要检测大量基因，则工作量巨大，耗时长久。 通过简单的，经过优化的实时定量PCR体系，如SuperArray的RT2ProfilerTM
Ceramide and Sphingosine-1-Phosphate Signaling in Embryonic Stem Cell Differentiation
Recent studies show that bioactive lipids are important regulators for stem cell survival and differentiation. The sphingolipid ceramide and its derivative, sphingosine-1-phosphate (S1P), can act synergistically on embryonic stem (ES) cell
TGF- Signaling in Embryonic Stem Cell-Derived Endothelial Cells
in humans and mice. Embryonic stem cell (ESC)-derived vascular progenitor cells have been shown to differentiate into both endothelial and mural cells. We showed that members of the TGF-β superfamily play important roles during differentiation of vascular
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