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Antioxidant and Pro-Oxidant Enzymes: ACADSB, CAT, GPX1, GPX2, SOD1, SOD2, SOD3, XDH.
Molecular Chaperones: Heat Shock Proteins: CRYAA, CRYAB, DNAJA1, DNAJA2, DNAJA3, DNAJA4, DNAJB1, DNAJB11, DNAJB12, DNAJB2, DNAJB4, DNAJB5, DNAJB6, DNAJB9, DNAJC1, DNAJC4, DNAJC5, DNAJC6, DNAJC7, DNAJC8, DNAJC9, HMOX1, HMOX2, HSPA12A, HSPA1A, HSPA1L, HSPA2, HSPA4 (HSP70), HSPA5 (GRP78), HSPA8, HSPA9, HSPB1 (HSP27), HSPB2, HSPB3, HSPD1, HSPE1, SERPINH1 (HSP47).
Other Molecular Chaperones: BAG1, CALR, CANX, CCT2, CCT3, CCT4, CCT5, CCT7, CCT8, CLU, HOPX, PPID, ST13, TCP1.
Xenobiotic Metabolism: Cytochrome P450s: CYP11A1, CYP17A1, CYP1A1, CYP1A2, CYP1B1, CYP11B2, CYP2C19, CYP2C9, CYP2D6, CYP2E1, CYP3A4, CYP2F1, CYP4A11, CYP4B1, CYP7A1, CYP7B1.
Other Genes Related to Xenobiotic Metabolism: CES1, EPHX2, FMO1, FMO4, FMO5, GSR, GSTA1, GSTA5, GSTM5.
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文献和实验PCR芯片，研究者可以同时研究大量基因，既可以进行某些特别感兴趣的信号通路的研究，也可以作为验证芯片结果的方法。 为了获得理想的实验结果，PCR芯片面临以下挑战：高特异性，高灵敏度和可重复性。高灵敏度或低检出限，在样品的总RNA量少，基因表达量低的情况下，也能检测出目的基因。高特异性，扩增产物严格保证基因特异性，避免非特异性产物，如引物二聚体的产生。可重复性，通过标准化的反应体系和实验方法，使得多人多次重复实验均能获得可靠的基因定量结果。 PCR芯片实验操作步骤 采用PCR芯片进行实验只需
Protein Misfolding and Cellular Stress: An Overview
of dysfunctional mitochondria by cellular cleaning systems, i.e., mitophagy or mitoptosis, and related to the generation and cellular effects of oxidatively modified proteins, which closes a vicious cycle of protein misfolding and oxidative stress.
A Systems Approach Demonstrating Sphingolipid-Dependent Transcription in Stress Responses
Microarray hybridization allows genome-wide screening of changes in mRNA levels under stress conditions. In Saccharomyces cerevisiae , this approach has demonstrated that responses to heat stress, oxidative stress, nutrient deprivation
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