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文献和实验Methods for Screening in Cystic Fibrosis
Cystic fibrosis (CF) is the most common lethal autosomal recessive disorder in Whites, with an incidence of approx 1 m 2500 live births and a carrier frequency of approx 1 in 25. Since the discovery of the cystic fibrosis transmembrane
Methods for the Study of Intermolecular and Intramolecular Interactions Regulating CFTR Function
CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) is a cAMP-activated chloride channel present on the apical surfaces of epithelial cells. This protein has been shown to be responsible for salt and water transport across epithelia
Measurement of NO and NO Synthase
2 ) or acidified VCl 3 for nitrite/nitrate reduction (see protocol 3 ) NO gas cylinder and stainless steel regulator (100 to 200 ppm NO in N 2 , for preparation of NO gas standards) and N 2 gas
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