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- 技术资料
- 英文名：
Piceatannol，SIRT1 activator
- 供应商：
研卉生物
- 规格：
5mg
Piceatannol
Aliases: 3,3’,4,5’-Tetrahydroxy-trans-stilbeneApplication: SIRT1 activator
MW = 244.2
C14H12O4
CAS 10083-24-6
>98% (TLC); NMR (Conforms)
A naturally occurring resveratrol analog. Inhibits non-receptor kinases Syk and Lyk (IC50 = ca. 10 M) (ref 1). Stimulates Sirt1 (ref 2).
Light pink powder. May be dissolved in DMSO (10 mg/ml); Ethanol (10 mg/ml).
1. CJ Seow et al. Eur. J. Pharmacol. 2002, 443:189
2. KT Howitz et al. Nature 2003, 425:191
其他 SIRT1 activator
SirtAct SIRT1 activator
Resveratrol SIRT1 activator
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文献和实验Methods to Investigate the Role of SIRT1 in Endothelial Senescence
Sirtuins are a family of proteins with NAD+ -dependent deacetylase or mono-ADP-ribosyltransferase activity. SIRT1, the mammalian ortholog most closely related to Sir2 (the first gene of this family discovered in yeast), exhibits anti
myz68mrq 想做细胞的Notch调控，常用的Notch激活剂有哪些啊？ zhujoker 有rhNF-κB 参考下面2篇文献： Wnt和notch信号通路在肿瘤干细胞自我更新中的作用 ， myz68mrq 谢谢回复。现在有研究者使用Recombinant Rat Jagged 1 Fc Chimera，作为Notch的激活剂，不知在选择上有何不同？
SILAC-Based Quantification of Sirt1-Responsive Lysine Acetylome
, in combination with affinity enrichment of acetyllysine peptides and mass spectrometry, to study the dynamic changes of the Lysine acetylome in response to Sirt1. The method should be applicable to quantify changes to other post translational modifications
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