手机验证
4°C
详见说明
Dipyridamole
充足
杭州昊鑫生物
58-32-2
100mg
生物活性 | Dipyridamole is an orally active phosphodiesterase (PDE) inhibitor. Dipyridamole also is an antiplatelet agent used in secondary prophylaxis against stroke. Dipyridamole can induce cancer cell-specific apoptosis[1][2][3]. |
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IC50 & Target | PDE |
体外研究 (In Vitro) |
Dipyridamole (5 μM; 15 min) results in a 2.5-fold increase in intracellular cAMP levels in OCI-AML-3 cells[2]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Apoptosis Analysis[2]
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体内研究 (In Vivo) |
Dipyridamole (10 mg/kg; p.o. once daily for 18 d) mitigates tumor growth, ameliorated concurrent alterations in blood circulation and tumor tissues, and platelet infiltration in tumor tissues[3]. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
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Clinical Trial |
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分子量 | 504.63 |
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Formula | C24H40N8O4 |
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CAS 号 | |||||||||||||||||
中文名称 | 双嘧达莫;二吡待摩;双密达莫 |
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运输条件 | Room temperature in continental US; may vary elsewhere. |
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储存方式 | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
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溶解性数据 | In Vitro: DMSO : ≥ 50 mg/mL (99.08 mM) H2O : 0.67 mg/mL (1.33 mM; Need ultrasonic) * "≥" means soluble, but saturation unknown. 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo: 请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百 |
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