- ￥900 - 1800
- 华拓生物
- 中国
- HT1610273
- 2025年07月15日
- FC
- Hamster2
- Mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CD80 (B7-1)
- 亚型：
Hamster IgG2
- 形态：
PBS pH 7.2, 0.09% NaN3, 0.2% BSA
- 保存条件：
Store at 4°C and protected from prolonged exposure to light. Do not freeze.
- 克隆性：
Monoclonal Antibody
- 标记物：
APC
- 适应物种：
Mouse
- 宿主：
Hamster2
- 应用范围：
FC
- 浓度：
Concentration：0.2 mg/ml
- 靶点：
Clone number：16-10A1
- 抗体英文名：
CD80 (B7-1) Antibody-APC；流式抗体
- 抗体名：
CD80 (B7-1) Antibody-APC；流式抗体
- 规格：
25/100 μg
克隆类型 ：Hamster Monoclonal Antibody；Clone number：16-10A1
货 号 ：HT1610273
规 格 ：25/100 μg ;
亚 型 ：
Hamster IgG2
浓 度 ：
Concentration：0.2 mg/ml
缓 冲 液 ：
PBS pH 7.2, 0.09% NaN3, 0.2% BSA
产品描述 ：
CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.
适用物种 ：
Mouse
应用范围 ：
FC
应用说明 ：
The amount of the reagent is suggested to be used ≤ 1.0 µg /10^6 cells in 100 µl
保存条件 ：
Store at 4°C and protected from prolonged exposure to light. Do not freeze.
标 记 物 ：
APC（其他荧光标记请咨询我们）
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文献和实验CD80 分子 CD80 常用单克隆抗体或代号： B7- 1,BB1 主要表达细胞： Ba,Mac,TStr [B] 分子质量(kDa)和结构： gp60(IgSF) 功 能： 活化B细胞抗原,CD28、CTLA- 4配体,提供T细胞共刺激信号 CD80 Aka B7-1, BB1 Ligand for T cell marker CD28 or CTLA4 (CD152
, while the second is provided by the B-cell activation antigens B7-1, or CD80 and B7-2, or CD86 by interaction with the T-cell surface molecules CD28 and CTLA4 Positive staining (normal): interdigitating dendritic cells in T zones of secondary lymphoid organs
Incorporation of Immunomodulators into Plasmid DNA Vaccines
(CD80, CD86, and CD40-ligand) may provide maturation signals to antigen-presenting cells (APC) to enhance their ability to present vaccine antigens, and result in an increased adaptive immune response (3 ,4 ). More recently, cytokines and chemokines
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