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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
4°C, sealed storage, away from moisture
- 英文名：
Fondaparin sodium; SR-90107A
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- 规格：
10 mM * 1 mL/1 mg/5 mg/10 mg/25 mg/50 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥2756.0 |
|---|---|---|---|
| 规格： | 1 mg | 产品价格： | ￥350.0 |
| 规格： | 5 mg | 产品价格： | ￥800.0 |
| 规格： | 10 mg | 产品价格： | ￥1450.0 |
| 规格： | 25 mg | 产品价格： | ￥3200.0 |
| 规格： | 50 mg | 产品价格： | ￥5400.0 |
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Fondaparinux sodium
CAS No. : 114870-03-0
MCE 国际站：Fondaparinux sodium
产品活性：Fondaparinux sodium 是一种抗凝血酶依赖性的 factor Xa 抑制剂。
研究领域：Metabolic Enzyme/Protease
作用靶点：Factor Xa
In Vitro: Fondaparinux sodium is the first agent of a new class of anticoagulants that selectively target factor Xa. For Fondaparinux, its IC50 values (anti-Xa IU/ml) are 0.59±0.05 for activated monocytes (ac-M) and 0.17±0.03 for monocyte-derived microparticles (MMPs).
In Vivo: Fondaparinux sodium has a linear, dose-dependent pharmacokinetic profile, which provides a highly predictable response. Fondaparinux sodium is 100% bioavailable, has a rapid onset of action, and has a half-life of 14 to 16 hours, allowing for sustained antithrombotic activity over a 24-hour period. The drug does not affect prothrombin time or activated partial thromboplastin time, nor does it affect platelet function or aggregation.
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文献和实验The synthetic pentasaccharide Arixtra or Fondaparinux is an indirect anti-Xa that effectively inhibits thrombin generation via its binding to anti-thrombin, the co-factor for Xa. A well-executed and designed clinical development
Sodium (23 Na) imaging has a place somewhere between 1 H-MRI and MR spectroscopy (MRS). Like MRS it potentially provides information on metabolic processes, but only one single resonance of ionic 23 Na is observed. Therefore pulse sequences
Na。原子量 23。所有植物都含有钠，但对茎叶植物来说恐不是不可缺少的。钠对包括甜菜在内的若干盐生植物的生长，以及对适应高盐环境的蓝藻类的生长都具有促进作用。尤其是对鱼腥藻（ Anabaena）是不可缺少的，在缺乏钾时钠可以部分地代替钾的作用。对许多动物来说，钠是维持体液渗透压不可缺少的成分，具有增加活细胞透性的作用。另外，对哺乳类来说，钠对血量的维持、体液的贮存、以及皮肤和肾脏的排泄都有夫系，这种钠的代谢是受副肾皮质激素（盐皮质激素）的调节。钠是脊椎动物血浆组成中的主要阳离子，在人体
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