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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Purified recombinant fragment of human FAK expressed in E. coli. <br>
- 亚型:
Mouse IgG1
- 形态:
Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
- 保存条件:
Store at -20°C
- 克隆性:
单克隆抗体
- 标记物:
见下方详细说明
- 适应物种:
H
- 宿主:
Mouse
- 应用范围:
WB
- 浓度:
见详细说明信息
- 靶点:
FAK (10H7A)
- 抗体英文名:
FAK (10H7A) Antibody
- 抗体名:
FAK (10H7A) Antibody
- 规格:
0.1 ml
FAK (10H7A) Antibody产品详细介绍:
| 产品名称: | FAK (10H7A) Antibody |
| 说明书: | 【点击查看详细说明及参考图片】 |
| 货号: | 253012 |
| 规格: | 0.1 ml |
| 产品描述: | FAK (Focal adhesion kinase) is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. FAK is concentrated at the basal edge of only basal keratinocytes that are actively migrating and rapidly proliferating in repairing burn wounds, activated and localized to the focal adhesions of spreading keratinocytes in culture. Thus, it has been postulated that FAK may have an important in vivo role in the re-epithelialization of human wounds. FAK protein tyrosine kinase activity has also been shown to increase in cells stimulated to grow by use of mitogenic neuropeptides or neurotransmitters acting through G protein-coupled receptors. |
| 克隆类型: | Mouse Monoclonal Antibody |
| 亚型: | Mouse IgG1 |
| 免疫原: | Purified recombinant fragment of human FAK expressed in E. coli. |
| 适用物种: | H |
| 应用范围: | WB |
| 应用说明: | WB: 1:500-1:2000; |
| 别名: | Focal adhesion kinase 1; FADK 1; Focal adhesion kinase-related nonkinase; FRNK; Protein phosphatase 1 regulatory subunit 71; PPP1R71; Protein-tyrosine kinase 2; p125FAK; pp125FAK FAK; FAK1; PTK2 |
| 形态: | Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide. |
| 保存条件: | Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment. |
| 参考文献: |
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文献和实验Quantification of Myocyte Chemotaxis: A Role for FAK in Regulating Directional Motility
in motility and a single-cell tracking assay to identify signals that drive the coordinated movement of these cells. These methods have proven effective to identify focal adhesion kinase (FAK) as an intracellular component that is critical for myocyte
Inflammation and Tumor Progression: A Lesson from TNF--Dependent FAK Signaling in Cholangiocarcinoma
Focal Adhesion Kinase (FAK) is implicated in a wide array of cellular processes and also involved in the production of matrix metalloproteinases (MMPs) which degrade extracellular matrix (ECM). We have shown that FAK plays a critical role
指仅对一种抗原决定基的纯粹的抗体。这类抗体不可能通过将抗原 胞的 Hybridoma,在试管内制成了纯粹的单克隆抗体。用某种抗原使动物产生免疫感应,对应于抗原之不同部分可制成各种不同的抗体复合体。然而,因为一个产生抗体的细胞,只能产生一种抗体,所以骨髓肿瘤细胞与产生抗体细胞间的细胞杂种,可形成边产生抗体边增殖的 hybridoma,将每个杂种细胞进行克隆(无性繁殖系)培养,则一个克隆的细胞群只由单种类产生同一抗体的细胞所组成,这样得到的就是单克隆抗体。此抗体在测定
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