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C1 Inhibitor (6C6)单克隆抗体

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  • ¥3000 - 3999
  • Abbiotec已认证
  • 美国
  • Cat. No. 250424
  • 2025年12月13日
  • E
  • Mouse
  • H
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      C1-inhibitor (C1INH) isolated from human plasma

    • 亚型

      Mouse IgG1/k

    • 形态

      Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.

    • 保存条件

      Store at 4°C.

    • 克隆性

      单克隆抗体

    • 标记物

      见下方详细说明

    • 适应物种

      H

    • 宿主

      Mouse

    • 应用范围

      E

    • 浓度

      见详细说明信息

    • 靶点

      C1 Inhibitor (6C6)

    • 抗体英文名

      C1 Inhibitor (6C6) Antibody

    • 抗体名

      C1 Inhibitor (6C6)抗体

    • 规格

      0.2 mg

    产品细节图片1
    C1 Inhibitor (6C6) Antibody产品详细介绍:
    产品名称: C1 Inhibitor (6C6) Antibody
    说明书: http://abbiotec.com/antibodies/c1-inhibitor-%286c6%29-antibody【参考图片】
    货号: 250424
    规格: 0.2 mg
    产品描述: C1-inhibitor (C1INH) functions as a regulator of the activation of the classical complement pathway and of the contact activation system of kinin generation and coagulation. Its primary biologically relevant target proteinases are C1r, C1s, coagulation factors XIa and XIIa, and plasma kallikrein. C1-inhibitor consists of one polypeptide chain and has a molecular mass of 104 kDa. Serum concentration has been determined to 180 µg/ml. This antibody is specific for human C1INH.
    克隆类型: Mouse Monoclonal Antibody
    亚型: Mouse IgG1/k
    免疫原: C1-inhibitor (C1INH) isolated from human plasma
    适用物种: H
    应用范围: E
    应用说明: Product Cat. No. 250424 reacts strongly in sandwich ELISA with C1INH in human serum/plasma and a polyclonal antibody, or in direct ELISA with C1INH coated directly onto the microtiter well. E: 1:250
    别名: C1 Inh; C1Inh; C1 esterase inhibitor; C1-inhibiting factor
    形态: Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.
    保存条件: Store at 4°C. Product is guaranteed 6 months from the date of shipment.
    参考文献:

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    产品细节图片2 产品细节图片3

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    图标文献和实验
    相关实验
    • C1 Inhibitor: Quantification and Purification

      C1 inhibitor is a multipotent serpin capable of inhibiting the classical and the lectin pathways of complement, the fibrinolytic system, and contact/kinin system of coagulation. Deficiency of C1 inhibitor manifest as hereditary angioedema

    • C1-Inhibitor: Antigenic and Functional Analysis

      The classical pathway of complement is activated in various diseases. A main inhibitor of this pathway is the serpin C1-inhibitor (C1-Inh), which regulates activation at the level of C1. C1-Inh also inhibits the mannan binding lectin (MBL

    • Nature Cancer I 生物标志物多参数评估mTLS预测实体瘤免疫治疗效果

      TLS 成熟度,需要对 CD8、CD4、CD20、CD21 和 CD23 进行多参数分析。 阻断 PD-1 受体与其主要配体 PD-L1 之间的相互作用具有显著抗癌作用,已有多种抗 PD-1 或抗 PD-L1 药物被批准用于多种实体瘤治疗。然而,大多数接受抗 PD-1 或抗 PD-L1 单克隆抗体的患者并没有从中获益。 免疫组织化学、肿瘤突变负荷 (TMB) 和微卫星不稳定性状态评估的 PD-L1 表达状态是迄今为止唯一被批准用于指导抗 PD-1 治疗的伴随诊断标志物。这些方法并不能有效区分出可能

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