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- 英文名:
COX-1 (ovine)
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文献和实验Preparation of Ovine Adenovirus Vectors
3 ) and others (4 –6 ) are therefore developing nonhuman adenoviruses as gene therapy vectors. Among these, vectors derived from the ovine adenovirus isolate 287 (OAV) have been found to deliver genes with high efficiency to several mammals. This chapter introduces
Production and Release Testing of Ovine Atadenovirus Vectors
. To ensure the potency and efficacy of such vectors and to obtain regulatory approval to administer them to humans, it is necessary to develop a suite of assays that provide quality assurance. New GDEPT vectors based on ovine atadenovirus and Escherichia coli
The discovery of two isoforms of the cyclooxygenase (COX) enzyme, COX-1 and COX-2, has provided the rationale for development of selective COX-2 inhibitors as a class of safer drugs for the treatment of pain, symptoms of osteoarthritis
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