- 询价
- Cell Signaling Technology
- 2647
- USA
- 2026年05月28日
- W, IHC-P
- H
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- 文献和实验
- 技术资料
- 抗体英文名：
α-Synuclein (Syn204) Mouse mAb
- 抗原：
human recombinant α-synuclein and the epitope maps to the amino-terminus of the protein
- 应用范围：
W, IHC-P
- 适应物种：
H
- 供应商：
CST
- 保质期：
详见说明书
- 库存：
大量
- 级别：
详见MSDS文件
- 是否单克隆：
1
- 保存条件：
-20°c
- 规格：
40 ul (4 western blots)/100 ul (10 western blots)/carrier free & custom formulation / quantity
| 规格： | 产品价格： | ￥请询价 | |
|---|---|---|---|
| 规格： | 40 ul (4 western blots) | 产品价格： | ￥请询价 |
| 规格： | 100 ul (10 western blots) | 产品价格： | ￥请询价 |
| 规格： | carrier free & custom formulation / quantity | 产品价格： | ￥请询价 |
pathway more info application references datasheet PDF MSDS PDF protocols
Applications Key: W=Western Blotting IHC-P=Immunohistochemistry (Paraffin) IF-P=Immunofluorescence (Paraffin)
Reactivity Key: H=Human
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on 100% sequence homology.
| Applications | Reactivity | Sensitivity | MW (kDa) | Isotype |
|---|---|---|---|---|
| W IHC-P | H | Endogenous | 18 | Mouse IgG2a |
| Protocols |
|
|---|---|
| Specificity / Sensitivity | α-Synuclein (Syn204) Mouse mAb detects endogenous levels of total synuclein protein. α-Synuclein (Syn204) Mouse mAb detects recombinant α but not β-synuclein (Giasson, B.I. et al., 2000). |
| Source / Purification | Monoclonal antibody is produced by immunizing animals with human recombinant α-synuclein and the epitope maps to the amino-terminus of the protein. Western Blotting
Western blot analysis of extracts from human cerebellum and HeLa cells, using α-Synuclein (Syn204) Mouse mAb. IHC-P (paraffin)
Immunohistochemical analysis of paraffin-embedded human brain, using α-Synuclein (Syn204) Mouse mAb. IF-P
Confocal immunofluorescent image of human Alzheimer's brain labeled with α-Synuclein (Syn204) Mouse mAb (red) and β-Amyloid Antibody #2454 (green). Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye). |
| Background | α-Synuclein is a protein of 140-amino acids expressed abundantly in the brain. α-Synuclein is also the main component of pathogenic Lewy bodies and Lewy neurites. Research studies have shown that mutations of the α-synuclein gene are linked to Parkinson's disease (1). |
| Application References |
Have you published research involving the use of our products? If so we'd love to hear about it. Please let us know ! |
| Companion Products |
For Research Use Only. Not For Use In Diagnostic Procedures. |
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文献和实验(adjust pH to 7.8 with Binding buffer; red color) to the Protein A column.Mouse antibodies of the IgG1 subclass do not have a high affinity for protein A. Purification on protein A beads using standard conditions will yield approximately 1/10
Using the Generic Synteny Browser (GBrowse_syn)
, the Generic Synteny Browser (GBrowse_syn) allows the comparison of colinear regions of multiple genomes using the familiar GBrowse?style Web page. Like GBrowse, GBrowse_syn can be configured to display any organism, and is currently the synteny browser used
Purification of mAb (IgG) by Chang-Duk Jun, 03/14/2000 Purpose Materials Antibody 7E3 , 2L sup grown in flasks, frozen and thawed overnight. BioRad Affi-Gel Protein A MAPS II Buffers
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