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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
The antiserum was produced against synthesized peptide derived from human Caspase 3.
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
- 克隆性:
Polyclonal
- 标记物:
Unconjugated
- 适应物种:
Human, Mouse, Rat
- 保质期:
12 months from the shipping date of the product.
- 抗原来源:
Human
- 目录编号:
GTX86952
- 级别:
Primary Antibodies
- 库存:
Available
- 供应商:
GeneTex
- 宿主:
Rabbit
- 应用范围:
WB, IHC-P, IHC
- 浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
- 靶点:
Caspase 3 (cleaved Asp175)
- 抗体英文名:
Caspase 3 (cleaved Asp175) antibody
- 抗体名:
Caspase 3 (cleaved Asp175) 抗体
- 规格:
100 μg
WB analysis of 293 cells treated with Etoposide (25uM, 60mins) lysate using GTX86952 Caspase 3 (cleaved Asp175) antibody.
IHC-P analysis of human lung carcinoma tissue using GTX86952 Caspase 3 (cleaved Asp175) antibody.
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文献和实验Huang ST et al., Sci Rep 2017 (PMID:28106052)
Zheng Y et al., Int J Biol Sci 2016 (PMID:26722223)
Huang ST et al., Am J Chin Med 2016 (PMID:27776427)
Dong Y et al., J Nat Prod 2012 (PMID:22304236)
Qu J et al., Clin Exp Pharmacol Physiol 2015 (PMID:26718307)
Sun Z et al., Front Cell Neurosci 2022 (PMID:35928572)
Yuan-Kun Tu et al., Curr Neurovasc Res 2021 (PMID:34645375)
Xu C et al., Oxid Med Cell Longev 2021 (PMID:34970414)
Du D. et al., Journal of Functional Foods 2021 84()
Zhang J et al., Mediators Inflamm 2021 (PMID:33958974)
Li D et al., Life Sci 2021 (PMID:33811894)
Huang C et al., BMC Complement Med Ther 2020 (PMID:32126993)
Yan J et al., Life Sci 2020 (PMID:33065148)
Li M et al., Cancer Manag Res 2020 (PMID:33061608)
Ahn CR et al., Biomedicines 2020 (PMID:32957430)
Xu Y et al., Aging (Albany NY) 2020 (PMID:32701482)
Wang YY et al., ACS Omega 2020 (PMID:32258937)
Tan YJ et al., Ther Adv Med Oncol 2019 (PMID:31632470)
Yi Jer Tan et al., Therapeutic Advances in Medical Oncology 2019 (Epub)
Chang CS et al., Sci Rep 2019 (PMID:31366973)
Dasgupta A et al., IUBMB Life 2019 (PMID:30977280)
Si W et al., 3 Biotech 2019 (PMID:30863710)
Yu H et al., Microcirculation 2019 (PMID:30801897)
Chen CC et al., Cancers (Basel) 2018 (PMID:30201872)
Chen CC et al., Cell Death Dis 2018 (PMID:29749376)
Yan J et al., J Photochem Photobiol B 2018
Omer FAA et al., Tumour Biol 2017 (PMID:29110583)
He Y et al., FASEB J 2017 (PMID:28420695)
[3] 。但据报道,MCF-7 人乳腺癌细胞系中,因在 CASP-3 基因 exon 3 中存在 47bp 的缺失而不表达 caspase 3 蛋白[4] 。前体形式的 caspase-3 由一个前端功能区(prodomain)和一大一小两个催化亚单位构成。在特定的刺激比如配体受体互作、生长因子匮乏和细胞功能抑制剂等的作用下,未活化的酶原形式的 caspase-3 在 Asp-28/Ser-29(N 端功能前区)以及 Asp-175/Ser-176(大小亚基之间)被剪切活化,转变为活化的 p17 大亚
【求助】caspase-3抗体与激活型caspase-3抗体
环佩从容 要做下一步实验啦,这两个抗体选哪个呀,目前研究有没有区分哪一个更好点啊 ronaldo_zj 楼主您好。 1. 楼主需要知道Pro caspase-3以及Cleaved caspase-3的功能以及检测手段,不是说哪个好那个不好的问题,而是根据你的课题需要检测何种片段的问题。请楼主先具体查阅关于caspase活化的文献后再定好实验计划; 2. 目前多数研究均认为Cleaved
Neoepitope Antibodies Against MMP-Cleaved and Aggrecanase-Cleaved Aggrecan
in studies determining the contribution of matrix metalloproteinases (MMPs) and aggrecanases to aggrecanolysis. In particular, an antibody to the A374 RGSV N terminus was instrumental in the landmark discovery of the aggrecanases, ADAMTS-4 and ADAMTS-5
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