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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
A synthetic peptide corresponding to a N-terminal region of Human SF3B1
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
- 克隆性:
Polyclonal
- 标记物:
Unconjugated
- 适应物种:
Human
- 保质期:
12 months from the shipping date of the product.
- 抗原来源:
Human
- 目录编号:
GTX47328
- 级别:
Primary Antibodies
- 库存:
Available
- 供应商:
GeneTex
- 宿主:
Rabbit
- 应用范围:
WB
- 浓度:
0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)
- 靶点:
SF3B1
- 抗体英文名:
SF3B1 antibody, N-term
- 抗体名:
SF3B1 抗体, N-term
- 规格:
50 μg
WB analysis of HeLa cells using GTX47328 SF3B1 antibody at 0.2-1μg/ml.
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文献和实验In the field of therapeutic recombinant proteins, monoclonal antibodies (mAbs) have achieved a rising success with more than 30 mAbs that have reached the market in the past 20 years. From a structural standpoint, one of the most important
to protect the antibody. These should be stored in smaller aliquots (about 1 ml) and frozen for long term storage though the protected solution is also stable for months at four degrees. Ascites fluid: This is a bit more problematic as it may contain
施一公团队又出新作!进一步解析人类 U2 snRNP 组装过程,提供癌症突变机制新见解
通过其 N 端扩展序列锚定在核心上。与这些序列基序相反,DDX42 的解旋酶结构域由两个 RecA 结构域组成,松散地连接在 SF3B1HEAT 的 C 端。 DDX42- SF3b 接口最显著的特点是将 DDX42 N-plug 放置在 SF3B1 的表面凹槽区域中,来自 N-plug 的带负电荷的氨基酸与来自 HR4-HR9 的带正电荷的残基形成了氢键 (H 键) 网络。与 N-plug 相反,DDX42 的 a−3 螺旋通过 SF3B1 的 HR5 与 HR3 的外部结合。 图片来源
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