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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
ATG12 antibody was raised against a 15 amino acid synthetic peptide from near the center of human ATG12.The immunogen is located within the first 50 amino acids of ATG12.
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
- 克隆性:
Polyclonal
- 标记物:
Unconjugated
- 适应物种:
Human, Mouse, Rat
- 保质期:
12 months from the shipping date of the product.
- 抗原来源:
Human
- 目录编号:
GTX31769
- 级别:
Primary Antibodies
- 库存:
Available
- 供应商:
GeneTex
- 宿主:
Rabbit
- 应用范围:
WB, IHC-P, ELISA
- 浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
- 靶点:
ATG12
- 抗体英文名:
ATG12 antibody
- 抗体名:
ATG12 抗体
- 规格:
100 μg
IHC-P analysis of human brain tissue using GTX31769 ATG12 antibody.
Working concentration : 20 μg/ml
IHC-P analysis of human brain tissue using GTX31769 ATG12 antibody.
Working concentration : 2.5 μg/ml
WB analysis of mouse heart tissue lysate in (A) the absence and (B) the presence of blocking peptide using GTX31769 ATG12 antibody.
Working concentration : 1 μg/ml
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文献和实验Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
性意味着到现在为止科学家们对此知之甚少,直到 20 世纪 90 年代早期研究者 YoshinoriOhsumi 进行了一系列实验,他利用面包酵母进行研究鉴别出于对自体吞噬作用非常重要的关键基因,随后他进行了大量研究阐明了酵母细胞中自体吞噬作用发生的分子机制,并且也在我们的机体细胞中发现了类似更为复杂的机制。新研究将焦点放在 ATG12 和 ATG5 这两种蛋白的结构和功能上。这些蛋白正确连接可形成一种称作自噬体(autophagosome)的细胞器。自噬体可像垃圾袋一样移除有毒物质,通过再循环向细胞
The importance of antibody molecules was first recognized in the 1890s, when it was shown that immunity to tetanus and diphtheria was caused by antibodies against the bacterial exotoxins (1 ). Around the same time, it was shown that antisera
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