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- 文献和实验
- 技术资料
- 免疫原:
The immunogen recognized by this antibody maps to a region between residue 475 and 525 of human ATPase, Ca++ transporter, cardiac muscle, slow twitch 2 using the numbering given in entry NP_733765.1 (GeneID 488).
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
- 克隆性:
Polyclonal
- 标记物:
Unconjugated
- 适应物种:
Human, Mouse, Rat, Rabbit, Pig
- 保质期:
12 months from the shipping date of the product.
- 抗原来源:
Human
- 目录编号:
GTX23625
- 级别:
Primary Antibodies
- 库存:
Available
- 供应商:
GeneTex
- 宿主:
Rabbit
- 应用范围:
WB, IP, ChIP assay
- 浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
- 靶点:
SERCA2 ATPase
- 抗体英文名:
SERCA2 ATPase antibody
- 抗体名:
SERCA2 ATPase 抗体
- 规格:
50 μl
IP analysis of 293T cell lysate using GTX23625 SERCA2 ATPase antibody.
IP protein : 0.5 -1.0 mg
Dilution : 1 μg/ml for WB ; 0.5-1 mg lysate / 6μg antibody for IP reaction
Loading: 20% of IP loaded
WB analysis of HeLa, 293T, Jurkat, TCMK-1, and NIH3T3 cell lysates (in NETN lysis buffer) using GTX23625 SERCA2 ATPase antibody.
Loading : 50μg
Dilution : 1 μg/ml
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文献和实验Cantero-Recasens G et al., Hum Mol Genet 2010 (PMID:19819884)
Ca2+ signaling plays an essential role in several functions of cardiac myocytes. Transient rises and reductions of cytosolic Ca2+ , permitted by the sarcoplasmic reticulum Ca2+ ATPase (SERCA2) and other proteins, control each cycle
Transgenic Mouse Models for Cardiac Dysfunction by a Specific Gene Manipulation
The sarcoplasmic reticulum Casn+2 ATPase (SERCA) plays a pivotal role in calcium cycling and the beat-to-beat function of the heart. Recent studies have shown that decreased expression and activity of SERCA are associated with end-stage heart
依据。 06 靶点:SERCA2/ATP2A2 应用:急性肾损伤(AKI)治疗的潜在靶点 来源:SERCA2 deficiency in tubular epithelial cells drives ferroptosis in acute kidney injury by regulating endoplasmic reticulum‑mitochondrial calcium homeostasis via voltage‑dependent anion
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