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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
A synthetic peptide (SPYVESEDAPPQKC) conjugated to KLH, corresponding to amino acids 327-339 of human n-Myc. [UniProt# P04198]
- 亚型:
IgG2a
- 形态:
Liquid
- 保存条件:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
- 克隆性:
Monoclonal
- 标记物:
Unconjugated
- 适应物种:
Human, Mouse
- 保质期:
12 months from the shipping date of the product.
- 抗原来源:
Human
- 目录编号:
GTX20057
- 级别:
Primary Antibodies
- 库存:
Available
- 供应商:
GeneTex
- 宿主:
Mouse
- 应用范围:
WB, ICC/IF, FACS, IP, ChIP assay, Gel supershift assays, MS
- 浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
- 靶点:
This does not react with c-Myc or L-Myc.
- 抗体英文名:
n-Myc antibody [NMYC-1]
- 抗体名:
n-Myc 抗体 [NMYC-1]
- 规格:
100 μg
ICC/IF analysis of NTERA-2 cells using GTX20057 n-Myc antibody [NMYC-1].
Green : primary antibody
Red : Actin
Blue : DAPI
Dilution : 1:50
WB analysis of human heart tissue lysate using GTX20057 n-Myc antibody [NMYC-1].
WB analysis of IMR-32 cell lysate using GTX20057 n-Myc antibody [NMYC-1].
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文献和实验Chromatin Immunoprecipitation Assays for Myc and N-Myc
Myc and N-Myc have widespread impacts on the chromatin state within cells, both in a gene-specific and genome-wide manner. Our laboratory uses functional genomic methods including chromatin immunoprecipitation (ChIP), ChIP-chip
CIP/WAF gene without binding DNA directly but through interaction with different transcription factors such as Sp1 and Miz-1 that recognize specific DNA sequences in the p21CIP/WAF promoter (Gartel et al., 2001 and Wu e al., 2003). N-Myc
性都远高于当前的免疫学方法,所需时间也已达到临床要求,这对于难于培养的病毒(乙肝),细菌(如结核、厌氧菌)和原虫(如梅毒螺旋体)等来说尤为适用。 3.癌基因的检测和诊断 虽然对癌基因的研究大部分还属于基础阶段,但癌变是由基因变异所导致的这一基本事实已无庸置疑,所以癌基因、抗癌基因入抗转移基因的研究,离开分子水平的诊断手段是无法进行的,临床上已可应用的例子有白血病残留细胞的定量(包括慢粒和急粒),肺癌中P53及Rb等抗癌基因的失活,神经质瘤N-myc基因的激活和表达。通过原位杂交观察特定癌
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