- ￥1700 - 4000
- GeneTex
- 美国
- GTX132407
- 2025年07月15日
- WB
- Rabbit
- Human, Mouse
企业认证
相关产品推荐更多 >
![Interferon gamma antibody [373] (FITC)](https://custom.dxycdn.com/trademd/upload/pic/2013/11/12/A1383891150.jpg!small.t.1)
![Cytokeratin 5 + 6 antibody [D5/16 B4]](https://img1.dxycdn.com/2022/0328/005/7943036624208300453-14.jpg!wh200)
![DAG1 / beta Dystroglycan antibody [43DAG1/8D5]](https://img1.dxycdn.com/2022/0328/636/3595042013397700453-14.jpg!wh200)
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Carrier-protein conjugated synthetic peptide surrounding mutant G12D of human K-Ras. The exact sequence is proprietary.
- 亚型：
IgG
- 形态：
Liquid
- 保存条件：
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
- 克隆性：
Polyclonal
- 标记物：
Unconjugated
- 适应物种：
Human, Mouse
- 保质期：
12 months from the shipping date of the product.
- 抗原来源：
Human
- 目录编号：
GTX132407
- 级别：
Primary Antibodies
- 库存：
Available
- 供应商：
GeneTex
- 宿主：
Rabbit
- 应用范围：
WB
- 浓度：
0.39 mg/ml (Please refer to the vial label for the specific concentration.)
- 靶点：
RAS (G12D Mutant)
- 抗体英文名：
RAS (G12D Mutant) antibody
- 抗体名：
RAS (G12D Mutant) 抗体
- 规格：
100 μl/25 μl
| 规格： | 100 μl | 产品价格： | ￥4000.0 |
|---|---|---|---|
| 规格： | 25 μl | 产品价格： | ￥1700.0 |
Non-transfected (–) and transfected (+) 293T whole cell extracts (30 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with RAS (G12D Mutant) antibody (GTX132407) diluted at 1:20000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
Various whole cell extracts (30 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with RAS (G12D Mutant Specific) antibody (GTX132407) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.
Non-transfected (–) and transfected (+) 293T whole cell extracts (30 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with RAS (G12D Mutant Specific) antibody (GTX132407) diluted at 1:20000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Tippimanchai DD et al., Oncoimmunology 2018 (PMID:29872579)
Holokai L et al., Cancers (Basel) 2020 (PMID:33348809)
Detection of K-ras and p53 Mutations by Mutant-Enriched PCR-RFLP
, since they fulfill many criteria that link their de novo appearance to the process of field cancerization (4 ). Oncogene mutations of the ras - and p53 -type are found in chronic smokers and patients with preneoplastic and neoplastic lesions
Interfering with Ras Signaling Using Membrane-Permeable Peptides or Drugs
During the last two decades since the first oncogene product called v-Src was identified as a constitutively activated mutant of a normal mitogenic gene (proto-oncogene) encoding a Tyr kinase called c-Src in early 1980s, it was firmly
种（如 EGFR 突变、ALK/ROS1 重排、KRAS 突变、和 BRAF 突变等），利用基因编辑技术在小鼠上引入该突变基因，使小鼠自发肺癌表型，这类模型可用于肺癌发生与转移机制的研究，以及抗肿瘤药物的筛选和评价。下面小编将主要为大家介绍两种常见的自发肺癌模型。 KRAS 突变肺癌模型 KRAS 基因是首个被确定的原癌基因，其编码的基因是一种小的 GTP 水解酶，通过在激活（GTP 结合）和失活（GDP 结合）构象之间循环来控制多个信号级联通路，与 HRAS、NRAS 同属于 Ras 超蛋白
技术资料暂无技术资料 索取技术资料
