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- Cell Signaling Technology
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- 2025年07月13日
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文献和实验Study of Substrate Specificity of MAPKs Using Oriented Peptide Libraries
screening combined with bioinformatics offers an alternative approach to predicting likely substrates of protein kinases through motif identification and database searching (4 –9 ). In this approach, degenerate peptide libraries containing an orienting Ser
). One of the most interesting issues is the possible development of miRNA therapeutics for development of anti-cancer molecules. In this respect appealing molecules are based on peptide nucleic acids (PNAs), displaying a pseudo-peptide backbone composed of N -(2-aminoethyl
Synthesis of Peptide‐Oligonucleotide Conjugates by Diels‐Alder Cycloaddition in Water
between diene‐5′ dT15 and maleimide‐Lys‐Glu‐Thr‐Ala‐Ala‐Ala‐Lys‐Phe‐Glu‐Arg‐Gln‐His‐Met‐Asp‐Ser‐Ser‐Thr‐Ser‐Ala‐Ala‐OH after 20 hr (C ), and 8 hr later after having added the amount of peptide equivalent to that of unreacted oligonucleotide (D ). See Basic
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