- ￥2310 - 3870
- Sino Biological
- 北京
- 10173-H08H
- 2026年01月26日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
-20℃ to -80℃
- 保质期：
12个月
- 英文名：
Recombinant Human COMP Protein (His Tag)
- 库存：
99
- 供应商：
北京义翘神州科技股份有限公司
- 规格：
50.00 µg/100.00 µg
| 规格： | 50.00 µg | 产品价格： | ￥2310.0 |
|---|---|---|---|
| 规格： | 100.00 µg | 产品价格： | ￥3870.0 |
人 COMP蛋白|COMP protein|COMP(Human, C-His)（产品说明）
蛋白名称：COMP蛋白, COMP protein
蛋白构建：A DNA sequence encoding the human COMP (NP_000086.2) precusor (Met 1-Ala 757) was expressed with a C-terminal polyhistidine tag.
表达宿主：HEK293 Cells
蛋白纯度：> 80 % as determined by SDS-PAGE
蛋白活性：Measured by its ability to induce adhesion of ATDC5 mouse chondrogenic cells.When cells are added to COMP-coated plates (0.625 μg/mL and 100 μL/well), approximately >30% cells will adhere specifically after 60 minutes at 37℃.
蛋白内毒素：< 1.0 EU per μg of the protein as determined by the LAL method
预测N端：Gln 21
蛋白分子量：The mature form of human COMP consists of 748 amino acids after removal of the signal peptide and predicts a molecular mass of 82.4 kDa. As a result of glycosylation, the apparent molecular mass of rhCOMP is approximately 120-130 kDa in SDS-PAGE under reducing conditions.
蛋白NP号：NP_000086.2
蛋白氨基酸序列：Met1-Ala757
蛋白标签：C-His
蛋白保存条件：Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
蛋白名称：COMP蛋白, COMP protein
蛋白构建：A DNA sequence encoding the human COMP (NP_000086.2) precusor (Met 1-Ala 757) was expressed with a C-terminal polyhistidine tag.
表达宿主：HEK293 Cells
蛋白纯度：> 80 % as determined by SDS-PAGE
蛋白活性：Measured by its ability to induce adhesion of ATDC5 mouse chondrogenic cells.When cells are added to COMP-coated plates (0.625 μg/mL and 100 μL/well), approximately >30% cells will adhere specifically after 60 minutes at 37℃.
蛋白内毒素：< 1.0 EU per μg of the protein as determined by the LAL method
预测N端：Gln 21
蛋白分子量：The mature form of human COMP consists of 748 amino acids after removal of the signal peptide and predicts a molecular mass of 82.4 kDa. As a result of glycosylation, the apparent molecular mass of rhCOMP is approximately 120-130 kDa in SDS-PAGE under reducing conditions.
蛋白NP号：NP_000086.2
蛋白氨基酸序列：Met1-Ala757
蛋白标签：C-His
蛋白保存条件：Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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文献和实验该产品被引用文献
1, Wang, C; et al. ADAMTS7 degrades Comp to fuel BMP2‐dependent osteogenic differentiation and ameliorate oncogenic potential in osteosarcomas. FEBS open bio, PMID: 32692461
2, Huang, J; et al. Downregulation of NNMT affects trophoblast function via inhibiting COMP/CD36/ERK1/2 axis in recurrent spontaneous abortion. Cellular signalling, PMID: 40274084
3, Liu, F; et al. Single-cell profiling of bone metastasis ecosystems from multiple cancer types reveals convergent and divergent mechanisms of bone colonization. Cell genomics, PMID: 40412393
2, Huang, J; et al. Downregulation of NNMT affects trophoblast function via inhibiting COMP/CD36/ERK1/2 axis in recurrent spontaneous abortion. Cellular signalling, PMID: 40274084
3, Liu, F; et al. Single-cell profiling of bone metastasis ecosystems from multiple cancer types reveals convergent and divergent mechanisms of bone colonization. Cell genomics, PMID: 40412393
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重组人 COMP蛋白 (His 标签)
￥2310 - 3870
