小鼠 ACVR2B蛋白|ACVR2B protein|ACVR2B(Mouse, C-human IgG1-Fc & His)(产品说明)
蛋白名称:ACVR2B蛋白, ACVR2B protein
蛋白构建:A DNA sequence encoding the extracellular domain (Met 1-Thr 134) of mouse ACVR2B (NP_031423.1) precursor was fused with the Fc region of human IgG1 at the C-terminus.
表达宿主:HEK293 Cells
蛋白纯度:> 97 % as determined by SDS-PAGE
蛋白活性:1. Measured by its ability to bind biotinylated Human INHBA-his (Cat:10429-H08H) in functional ELISA.2. Measured by its ability to bind biotinylated mouse INHBA-his (Cat:50659-M08H) in functional ELISA.3. Measured by its ability to neutralize Activin-mediated inhibition on MPC11 cell proliferation. The ED50 for this effect is typically 10-50 ng/mL in the presence of 10 ng/mL recombinant Activin A.
蛋白内毒素:< 1.0 EU per μg of the protein as determined by the LAL method
预测N端:Ser l9
蛋白分子量:The recombinant mouse ACVR2B/Fc is a disulfide-linked homodimer after removal of the signal peptide. The reduced monomer consists of 364 amino acids and has a predicted molecular mass of 41 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rmACVR2B/Fc monomer is approximately 60-65 kDa due to glycosylation.
蛋白NP号:NP_031423.1
蛋白氨基酸序列:Met1-Thr134
蛋白标签:C-human IgG1-Fc & His
蛋白保存条件:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.