- ￥297 - 887
- TargetMol
- 美国
- T6588
- 2025年07月14日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
零下80~20°C
- 保质期：
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名：
Mitoxantrone
- 库存：
10
- 供应商：
TargetMol
- CAS号：
65271-80-9
- 规格：
25 mg/1 mL/100 mg/50 mg/200 mg
| 规格： | 25 mg | 产品价格： | ￥297.0 |
|---|---|---|---|
| 规格： | 1 mL | 产品价格： | ￥373.0 |
| 规格： | 100 mg | 产品价格： | ￥617.0 |
| 规格： | 50 mg | 产品价格： | ￥418.0 |
| 规格： | 200 mg | 产品价格： | ￥887.0 |
Product Introduction
Bioactivity
英文名:Mitoxantrone
描述:Mitoxantrone (mitozantrone) is an inhibitor of topoisomerase II (Topo II), an inhibitor of protein kinase C (PKC) (IC50=8.5 μM). Mitoxantrone has antitumor activity for the treatment of acute myeloid leukemia, hepatocellular carcinoma, and breast cancer.
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文献和实验An In Vitro Transcription Assay for Probing Drug-DNA Interactions During Active Transcription of DNA
Many of the anticancer chemotherapeutic agents in current clinical use are known to interact strongly with DNA (e.g., Adriamycin, cis-platinum, melphalan, mitomycin C, and mitoxantrone). Although the exact mechanism of action remains unresolved
Continuous Infusion of Antisense Phosphorothioate Therapeutics
Current therapy for acute myelogenous leukemia (AML) includes induction with Ara-C and an anthracycline, such as daunorubicin, idarubicin, or mitoxantrone. Unfortunately, most patients relapse from initial remission. Nearly one-fifth of early
Transcriptional Footprinting of DrugDNA Interactions
There are now approx 50 registered anticancer drugs that are in routine clinical use as chemotherapeutic agents (1 –3 ). Of these, over half are known to interact with DNA, either by intercalation (e.g., doxorubicin, mitoxantrone), groove
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