- ￥600 - 1600
- Abbiotec
- 美国
- 300120
- 2025年07月11日
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- 详细信息
- 技术资料
- 保存条件：
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
- 保质期：
参照说明书可保存1-2年
- 英文名：
Beta-arrestin 1/2 Peptide
- 库存：
一定量库存
- 供应商：
华拓生物
- 规格：
0.1 mg
| 产品名称： | Beta-arrestin 1/2 Peptide |
| 产品链接： | http://www.abbiotec.com/peptides/beta-arrestin-12-peptide |
| 货号： | 300120 |
| 规格： | 0.1 mg |
| 产品描述： | Beta-arrestins function in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta-arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein. Beta-arrestin binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin-associated sorting proteins) and recruiting the GPRCs to the adaptor protein 2 complex 2 (AP-2) in clathrin-coated pits (CCPs). This antibody recognizes beta-arrestin-1 and beta-arrestin-2. The extent of beta-arrestin involvement appears to vary significantly depending on the receptor, agonist and cell type. |
| 序列： | The synthetic peptide used to raise the antibody Cat. No. 251344 is selected from a sequence within the center region of human beta-arrestin 1/2. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended. |
| 分子式： | C70H125N25O19 |
| 分子量： | 1620.9 g/mol |
| 纯度： | Purity > 80% by HPLC |
| 别名： | beta-arrestin 1; beta-arrestin 2; beta-arrestin 1/2; Beta-arrestin-1/2; Beta-arrestin-1; Arrestin beta-1; ARRB1; Beta-arrestin-2; Arrestin beta-2; ARRB2 |
| 形态： | Each vial contains 0.1 ml peptide in deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect. |
| 溶解方法： | Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile. |
| 保存方法： | Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. |
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Beta-arrestin 1/2 Peptide
￥600 - 1600
