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- 2025年12月05日
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- 文献和实验
- 技术资料
- 保存条件：
4°C, sealed storage, away from moisture and light
- 英文名：
Doxycycline hydrochloride hemiethanolate hemihydrate; WC2031
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
24390-14-5
- 规格：
10 mM * 1 mL/100 mg/1 g/5 g/10 g/25 g/50 g
| 规格： | 10 mM * 1 mL | 产品价格： | ￥500.0 |
|---|---|---|---|
| 规格： | 100 mg | 产品价格： | ￥400.0 |
| 规格： | 1 g | 产品价格： | ￥500.0 |
| 规格： | 5 g | 产品价格： | ￥750.0 |
| 规格： | 10 g | 产品价格： | ￥1320.0 |
| 规格： | 25 g | 产品价格： | ￥2645.0 |
| 规格： | 50 g | 产品价格： | ￥3850.0 |
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Doxycycline hyclate
CAS No. : 24390-14-5
MCE 国际站：Doxycycline hyclate
产品活性：Doxycycline hyclate 是一种具有口服活性的四环素抗生素，是广谱的金属蛋白酶 (MMP) 抑制剂，具有抗菌活性和抗癌细胞增殖活性。
研究领域：Metabolic Enzyme/Protease | Anti-infection
作用靶点：Antibiotic | MMP | Bacterial | Parasite
In Vitro: Doxycycline hyclate (0.01-10 µg/mL, 4 d) affects growth of glioma cells only under high concentrations.
Doxycycline hyclate (0.01-10 µg/mL, 24 h) decreases MT-CO1 protein content with concentrations of 1 µg/mL and higher in SVG cells.
Doxycycline hyclate (100 ng/mL, 1 µg/mL; 24 h) reduces proliferation of human cell lines.
Doxycycline hyclate (0-250 μM, 72 h) inhibits cell viability of breast cancer cells .
In Vivo: Doxycycline hyclate (oral gavage; 200 or 800 mg/kg; once daily; 3 months) reduces MMP-9 activity in untreated HT mice in a dose-dependent manner.
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文献和实验Doxycycline Regulated Lentiviral Vectors
Lentiviral vectors are a powerful tool to achieve regulated expression of transgenes in vivo and in vitro. The doxycycline-inducible system is well characterized and can be used to regulate expression mediated by lentiviral vectors
a doxycycline-inducible floxed Cre, which replaces itself with an incoming floxed gene of interest. The derivative cell lines, selected in G418, thus bear doxycycline-inducible transgenes. We provide detailed methods for performing ICE recombination
Extrachromosomal Inducible Expression
Inducible expression systems are very convenient for proteins that induce strong side effects such as retardation of growth or development and are essential for the expression of toxic proteins. In this chapter we describe the doxycycline
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