H-Glu-OtBu,45120-30-7

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H-Glu-OtBu

CAS No. : 45120-30-7

MCE 国际站：H-Glu-OtBu

产品活性：H-Glu-OtBu 是不可降解 (non-cleavable) 的 ADC linker，用于合成抗体偶联活性分子 (ADCs)。H-Glu-OtBu 也是一个基于烷基链 (alkyl chain) 的 PROTAC linker，可用于合成 PROTAC。

研究领域：Antibody-drug Conjugate/ADC Related  |  PROTAC

作用靶点：ADC Linker  |  PROTAC Linkers

In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

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