15-Hydroxy-7-oxodehydroabietic

Enzyme-Linked Immunosorbent Assays of Zearalenone Using Polyclonal, Monoclonal and Recombinant Antibodies

Zearalenone (6-[10-hydroxy-6-oxo-trans -1-undecenyl]-β-resorcyclic acid lactone), also known as F-2 toxin, is an estrogenic mycotoxin that is produced by Fusarium graminearum (1 ). This fungus can infect cereal grains and can elaborate

Simultaneous In Situ Detection of DNA Fragmentation and RNA/DNA Oxidative Damage Using TUNEL Assay and Immunohistochemical Labeling for 8-Hydroxy-2-De

and/ or necrosis (1 –6 ). TUNEL technique is widely used, for instance, to study mechanisms underlying early development and morphogenesis (7 –14 ), aging (15 –24 ), cancer (25 ,5 ,25 –35 ) and neurodegenerative diseases (36 ,20 ,21 ,36 –44 ). TUNEL

异常放电的神经元——癫痫的始作俑者

-aminobutyric acid，GABA）受体基因 GABA 受体亚单位的基因突变与多种遗传性癫痫综合症相关。GABA 是中枢神经系统内抑制性递质，当脑内 GABA 的含量降低或异常会导致兴奋性递质含量相对升高，神经元异常兴奋，诱发癫痫。 2.  5-羟色胺（5-hydroxy tryptamine，5-HT）受体基因 癫痫的敏感性可能与5-HT受体基因的多态性有关。5-HT 是一种中枢神经系统递质，与其受体相结合后发挥生物活性，参与多种精神活动调节。当在传导过程出现异常时，会导致神经元的高度同步化异常放电