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- Sino Biological
- 11748-RP01
- 2025年08月12日
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100 µL
抗体种属：Human
抗体靶点：SIRT1
抗体应用：ELISA
抗原货号：11748-H07E
抗原描述：Recombinant Human SIRT1 protein (Catalog#11748-H07E)
抗体宿主：Rabbit
抗体Ig类型：Rabbit IgG
抗体纯化方法：Protein A
抗体制备：Produced in rabbits immunized with purified, recombinant Human SIRT1 (rh SIRT1; Catalog#11748-H07E; NP_036370.2; Met193-Ser747). Total IgG was purified by Protein A affinity chromatography.
抗体特异性：Human SIRT1
抗体保存：This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
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文献和实验Methods to Investigate the Role of SIRT1 in Endothelial Senescence
Sirtuins are a family of proteins with NAD+ -dependent deacetylase or mono-ADP-ribosyltransferase activity. SIRT1, the mammalian ortholog most closely related to Sir2 (the first gene of this family discovered in yeast), exhibits anti
SILAC-Based Quantification of Sirt1-Responsive Lysine Acetylome
, in combination with affinity enrichment of acetyllysine peptides and mass spectrometry, to study the dynamic changes of the Lysine acetylome in response to Sirt1. The method should be applicable to quantify changes to other post translational modifications
through mathematical modeling. We further illustrate the approach using as case study the signaling module composed by the proteins p53, Sirt1, and the regulatory miRNA miR-34a. The model was used not only to investigate different possible designs of the silencing
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