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- 文献和实验
- 技术资料
- 保存条件：
-80℃
- 保质期：
2年
- 英文名：
HEPATIC S9 FRACTIONS
- 库存：
大量
- 供应商：
齐氏生物
- CAS号：
N/A
- 规格：
0.5ml、30mg/ml
肝细胞S9是肝实质细胞匀浆液的去线粒体上清液，包含了大量的CYPs等药物代谢酶，对于研究化合物的药物代谢和考察潜在的药物药物相互作用是非常有用的研究工具，同时也是食品、化妆品、化学品等致突变试验（Ames)重要试剂。
规格型号
产品优势
1. 技术优势：申报2项国家发明专利
2. 质量优势：批量制备、无菌，符合GLP试验需求
3. 客户优势：合作国内多家GLP安评机构、省级疾控、省级药检
4. 行业优势：入选丁香通2020“研选”推荐试剂
公司拥有冷冻保存的肝细胞和肝亚细胞组分的完整产品线，可用于ADME研究、诱导、抑制、体内清除率和代谢等研究。我们提供的肝亚细胞组分（包括肝微粒体、CYP450酶类、肝S9等），同时根据客户需要我们提供特定种属的定制化服务。
附：大鼠肝S9产品海报
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
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文献和实验该产品被引用文献
1) Int J Environ Res Public Health. 2018 Sep 2;15(9). pii: E1907. doi: 10.3390/ijerph15091907.
Evaluation by the Ames Assay of the Mutagenicity of UV Filters Using Benzophenone and Benzophenone-1.
Wang WQ1,2, Duan HX3, Pei ZT4,5, Xu RR6,7, Qin ZT8, Zhu GC9,10, Sun LW11,12.
2) Mutat Res Genet Toxicol Environ Mutagen. 2019 Feb;838:22-27. doi: 10.1016/j.mrgentox.2018.11.015. Epub 2018 Dec 1.
Genotoxicity evaluation of titanium dioxide nanoparticles using the mouse lymphoma assay and the Ames test.
Du X1, Gao S2, Hong L1, Zheng X3, Zhou Q4, Wu J5.
3) Mutat Res Genet Toxicol Environ Mutagen. 2019 Feb;838:22-27. doi: 10.1016/j.mrgentox.2018.11.015. Epub 2018 Dec 1.
Genotoxicity evaluation of titanium dioxide nanoparticles using the mouse lymphoma assay and the Ames test.
Du X1, Gao S2, Hong L1, Zheng X3, Zhou Q4, Wu J5.
4) Int J Environ Res Public Health. 2020 Feb 6;17(3). pii: E1025. doi: 10.3390/ijerph17031025.
Assessment of Biological Toxicity and Ecological Safety for Urban Black-Odor River Remediation.
Xu RR1,2, Pei ZT1,2, Wang WQ1,2, Zhang M1,2, Zhang LL1,2, Zhang J1,2, Wang WQ1,2, Sun LW1,2, Zhang YM3.
6) J Control Release. 2018 Jun 10;279:220-233. doi: 10.1016/j.jconrel.2018.04.034. Epub 2018 Apr 19.
Systemic delivery of BACE1 siRNA through neuron-targeted nanocomplexes for treatment of Alzheimer's disease.
Wang P1, Zheng X1, Guo Q1, Yang P1, Pang X1, Qian K1, Lu W2, Zhang Q3, Jiang X1.
7) EBioMedicine. 2018 Nov;37:246-258. doi: 10.1016/j.ebiom.2018.10.041. Epub 2018 Oct 23.
Salvianolic acid A targeting the transgelin-actin complex to enhance vasoconstriction.
Zhong W1, Sun B2, Gao W3, Qin Y1, Zhang H1, Huai L4, Tang Y4, Liang Y4, He L4, Zhang X4, Tao H4, Chen S2, Yang W2, Yang L2, Liu Y2, Liu H1, Zhou H5, Sun T6, Yang C7.
Evaluation by the Ames Assay of the Mutagenicity of UV Filters Using Benzophenone and Benzophenone-1.
Wang WQ1,2, Duan HX3, Pei ZT4,5, Xu RR6,7, Qin ZT8, Zhu GC9,10, Sun LW11,12.
2) Mutat Res Genet Toxicol Environ Mutagen. 2019 Feb;838:22-27. doi: 10.1016/j.mrgentox.2018.11.015. Epub 2018 Dec 1.
Genotoxicity evaluation of titanium dioxide nanoparticles using the mouse lymphoma assay and the Ames test.
Du X1, Gao S2, Hong L1, Zheng X3, Zhou Q4, Wu J5.
3) Mutat Res Genet Toxicol Environ Mutagen. 2019 Feb;838:22-27. doi: 10.1016/j.mrgentox.2018.11.015. Epub 2018 Dec 1.
Genotoxicity evaluation of titanium dioxide nanoparticles using the mouse lymphoma assay and the Ames test.
Du X1, Gao S2, Hong L1, Zheng X3, Zhou Q4, Wu J5.
4) Int J Environ Res Public Health. 2020 Feb 6;17(3). pii: E1025. doi: 10.3390/ijerph17031025.
Assessment of Biological Toxicity and Ecological Safety for Urban Black-Odor River Remediation.
Xu RR1,2, Pei ZT1,2, Wang WQ1,2, Zhang M1,2, Zhang LL1,2, Zhang J1,2, Wang WQ1,2, Sun LW1,2, Zhang YM3.
5) Hypoxia-triggered gene therapy: a new drug delivery system to utilize photodynamic-induced hypoxia for synergistic cancer therapy
Article in Journal of Materials Chemistry B 6(40) · September 2018 with 20 Reads6) J Control Release. 2018 Jun 10;279:220-233. doi: 10.1016/j.jconrel.2018.04.034. Epub 2018 Apr 19.
Systemic delivery of BACE1 siRNA through neuron-targeted nanocomplexes for treatment of Alzheimer's disease.
Wang P1, Zheng X1, Guo Q1, Yang P1, Pang X1, Qian K1, Lu W2, Zhang Q3, Jiang X1.
7) EBioMedicine. 2018 Nov;37:246-258. doi: 10.1016/j.ebiom.2018.10.041. Epub 2018 Oct 23.
Salvianolic acid A targeting the transgelin-actin complex to enhance vasoconstriction.
Zhong W1, Sun B2, Gao W3, Qin Y1, Zhang H1, Huai L4, Tang Y4, Liang Y4, He L4, Zhang X4, Tao H4, Chen S2, Yang W2, Yang L2, Liu Y2, Liu H1, Zhou H5, Sun T6, Yang C7.
研选
大鼠肝S9库 Rat Liver S9 Pooled 毒理实验 AMES细菌回复突变试验 CA染色体畸变试验 基因突变试验
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