BEND4 Antibody
Cat#:PL0306322
Isotype:Rabbit Polyclonal IgG
Immunogen:Peptide derived from human BEND4/CCDC4.
Purification: Immunogen affinity purified
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background:
BEND4 is a 530 amino acid protein that contains a BEN domain. BEND4 exists as five alternatively spiced isoforms and is considered a complete proteome. BEN domain mediates protein–DNA and protein–protein interactions during chromatin organization and transcription. BEN domain may play a role in organization of viral DNA during replication or transcription. The BEND4 gene maps to human chromosome 4p13. Representing approximately 6% of the human genome, chromosome 4 contains nearly 900 genes. Chromosome 4 reportedly contains the largest gene deserts (regions of the genome with no protein encoding genes) and has one of the two lowest recombination frequencies of the human chromosomes. Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease, is on chromosome 4.
Alternate Names:
BEN domain containing 4; BEN domain containing protein 4; BEN domain-containing protein 4; Bend4; BEND4_HUMAN; CCDC4; Coiled coil domain containing 4; Coiled coil domain containing protein 4; Coiled-coil domain-containing protein 4.
Specificity Reaction:Hu, Mo, Rat, Chi, Dog, Cow, Hor, , Sheep
Application Notes:E: 1:500-1000 IP: 1:20-100 IHC: 1:100-500 IF: 1:50-200
Storage :
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
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