phospho-HDAC2(Ser394) Antibody
Cat#:PL0303377
Isotype:Rabbit Polyclonal IgG
Immunogen:PhosphoPeptide derived from human HDAC2 around the phosphorylation site of Ser394.
Purification: Immunogen affinity purified
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background:
This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events.
Alternate Names:
HDAC2 (Phospho-Ser394); HDAC2 (phospho S394); HDAC2 (phospho Ser394); p-HDAC2 (Ser394); histone deacetylase 2; D10Wsu179e; EC 3.5.1.98; HD2; HDAC 2; Hdac2; histone deacetylase 2; RPD3; transcriptional regulator homolog RPD3; YAF1; YY1 associated factor 1; YY1 transcription factor binding protein; Yy1bp; HDAC2_HUMAN.
Specificity Reaction:Hu, Mo, Rat, Chi, Dog, Pig, Cow, Hor,
Application Notes:WB: 1:100-500 E: 1:500-1000 IP: 1:20-100 IHC: 1:100-500 IF: 1:100-500
Storage :
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
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