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- PL Laboratories
- 加拿大
- PL0301775
- 2025年07月15日
- WB: 1:100-500 E: 1:500-1000 IHC: 1:100-500 IF: 1:100-500
- Rabbit
- Hu, Mo, Rat, Chi, Dog, Cow, Hor
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- 详细信息
- 技术资料
- 免疫原：
Peptide derived from human CBP.
- 亚型：
Rabbit Polyclonal IgG
- 形态：
液态
- 保存条件：
保存于-20℃
- 克隆性：
多克隆
- 标记物：
无标记（PLlabs可供应生物素、酶、荧光素标记的抗体）
- 适应物种：
Hu, Mo, Rat, Chi, Dog, Cow, Hor
- 保质期：
按说明书条件可保存1-2年
- 抗原来源：
见详细说明资料
- 目录编号：
PL0301775
- 级别：
超纯
- 库存：
大量
- 供应商：
华拓生物
- 宿主：
Rabbit
- 应用范围：
WB: 1:100-500 E: 1:500-1000 IHC: 1:100-500 IF: 1:100-500
- 浓度：
1mg/ml
- 靶点：
CBP/CREBBP/TBP
- 抗体英文名：
CBP/CREBBP/TBP Antibody
- 抗体名：
CREB结合蛋白抗体
- 规格：
0.1ml
CBP/CREBBP/TBP Antibody
Cat#：PL0301775
Isotype:Rabbit Polyclonal IgG
Immunogen：Peptide derived from human CBP.
Purification: Immunogen affinity purified
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background：
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background：
This gene is ubiquitously expressed and is involved in the transcriptional coactivation of many different transcription factors. First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), this gene is now known to play critical roles in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition. The protein encoded by this gene has intrinsic histone acetyltransferase activity and also acts as a scaffold to stabilize additional protein interactions with the transcription complex. This protein acetylates both histone and non-histone proteins. This protein shares regions of very high sequence similarity with protein p300 in its bromodomain, cysteine-histidine-rich regions, and histone acetyltransferase domain. Mutations in this gene cause Rubinstein-Taybi syndrome (RTS). Chromosomal translocations involving this gene have been associated with acute myeloid leukemia.
Alternate Names：
CREB-binding protein; CREBBP; GTF2D; TATA binding factor; TATA box factor; TATA sequence binding protein; TBP; TFIID; Transcription initiation factor TFIID TBP subunit; GTF2D1; MGC117320; MGC126054; MGC126055; SCA 17; SCA17; TATA binding factor; TATA box binding protein; TATA box factor; TATA sequence binding protein; TBP; TF2D; TFIID; Transcription initiation factor TFIID TBP subunit; CBP/p300; CREB binding protein; Cyclic AMP-responsive enhancer binding protein; RSTS; RTS; Rubinstein-Taybi syndrome.
Specificity Reaction：Hu, Mo, Rat, Chi, Dog, Cow, Hor
Application Notes:WB: 1:100-500 E: 1:500-1000 IHC: 1:100-500 IF: 1:100-500
Storage ：
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
PLlabs公司可供应相应抗体的生物素、辣根过氧化物酶、荧光素（FITC、PE、 CY3、 CY5、 CY7、 PE- CY3/5/7)标记抗体，欢迎大家咨询订购。
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CREB结合蛋白抗体
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