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Recombinant Rat Interleukin-17

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  • ¥1680 - 3988
  • 美国ATCC
  • 美国/中国
  • 2025年11月05日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 库存

      大量

    • 供应商

      钰博生物

    • 细胞类型

      复苏

    • 组织来源

      见说明书

    • 物种来源

      人、大鼠、小鼠、、、、

    • 免疫类型

      请咨询销售人员

    • 细胞形态

      上皮样;多角形

    • 是否是肿瘤细胞

      见说明书

    • 器官来源

      见说明书

    • 运输方式

      干冰运输or活细胞运输

    • 年限

      见说明书

    • 生长状态

      贴壁生长

    Recombinant Rat Interleukin-17A
    Synonyms CTLA-8, IL-17, IL-17A, Cytotoxic T-lymphocyte-associated antigen 8, Interleukin-17A.
    Introduction IL17 is a proinflammatory cytokine produced by activated T cells. IL-17 regulates the activities of NF-kappaB and mitogen-activated protein kinases. Interleukin-17 can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
    Recombinant Rat Interleukin-17ADescription Interleukin-17A Rat Recombinant produced in E.Coli is a homodimeric, non-glycosylated polypeptide chain having a molecular mass of 30 kDa.
    The IL-17A Rat is purified by proprietary chromatographic techniques.
    Source Escherichia Coli.
    Physical Appearance Sterile Filtered White lyophilized (freeze-dried) powder.
    Formulation Lyophilized from a concentrated (1mg/ml) solution containing 10mM NaCitrate, pH-3.0.
    Recombinant Rat Interleukin-17ASolubility It is recommended to reconstitute the lyophilized Interleukin Rat 17A in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
    Stability Lyophilized Interleukin Rat 17A although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Rat IL17 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
    Please prevent freeze-thaw cycles.
    Purity Greater than 95.0% as determined by(a) Analysis by RP-HPLC.
    (b) Analysis by SDS-PAGE.
    Amino acid sequence MAVLIPQSSV CPNAEANNFL QNVKVNLKVL NSLSSKASSR RPSDYLNRST SPWTLSRNED PDRYPSVIWE AQCRHQRCVN AEGKLDHHMN SVLIQQEILV LKREPEKCPF TFRVEKMLVG VGCTCVSSIV RHAS.
    Recombinant Rat Interleukin-17ABiological Activity Rat IL-17A is fully biologically active when compared to standards via dose-dependent induction of IL-6 production in cultured mouse NIH 3T3 fibroblasts. The ED50 for recombinant rat IL-17A in this assay was 30ng/ml. The Specific Activity is 33333.33 units/mg.
    Usage CHI's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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