- ￥2400
- PLLABS
- 加拿大
- PL0402971
- 2025年07月15日
- WB: 1:100-500
- Rabbit
- Hu，Mo，Rat
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- 详细信息
- 技术资料
- 免疫原：
eptide corresponding to a sequence at the N-terminus of human Nicastrin.
- 亚型：
Rabbit Polyclonal IgG
- 形态：
液态
- 保存条件：
保存于-20℃
- 克隆性：
多克隆
- 标记物：
无标记（PLlabs可供应生物素、酶、荧光素标记的抗体）
- 适应物种：
Hu，Mo，Rat
- 保质期：
按说明书条件可保存1-2年
- 抗原来源：
见详细说明资料
- 目录编号：
PL0402971
- 级别：
超纯
- 库存：
大量
- 供应商：
华拓生物
- 宿主：
Rabbit
- 应用范围：
WB: 1:100-500
- 浓度：
1mg/ml
- 靶点：
NCSTN
- 抗体英文名：
NCSTN Antibody
- 抗体名：
NCSTN抗体
- 规格：
0.1ml
NCSTN Antibody
Cat#：PL0402971
Isotype:Rabbit Polyclonal IgG
Immunogen：eptide corresponding to a sequence at the N-terminus of human Nicastrin.
Purification: Immunogen affinity purified
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background：
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background：
Nicastrin, also known as NCSTN, is a protein that is a part of the gamma secretase protein complex. It is mapped to 1q23.2. This gene is not catalytically active, but instead promotes the maturation and proper trafficking of the other proteins in the gamma secretase protein complex, all of which undergo significant post-translational modification before becoming active in the cell. NCSTN encodes a Type I transmembrane glycoprotein that is an integral component of the multimeric gamma-secretase complex. The encoded protein cleaves integral membrane proteins, including Notch receptors and beta-amyloid precursor protein, and may be a stabilizing cofactor required for gamma-secretase complex assembly. The cleavage of beta-amyloid precursor protein yields amyloid beta peptide, the main component of the neuritic plaque and the hallmark lesion in the brains of patients with Alzheimer's disease.
Alternate Names：
Anterior pharynx defective 2 antibody;APH 2 antibody.
Specificity Reaction：Hu，Mo，Rat
Application Notes:WB: 1:100-500
Storage ：
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
PLlabs公司可供应相应抗体的生物素、辣根过氧化物酶、荧光素（FITC、PE、 CY3、 CY5、 CY7、 PE- CY3/5/7)标记抗体，欢迎大家咨询订购。
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NCSTN Antibody
￥2400
