RAIG1 Antibody

RAIG1 Antibody

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  • 询价
  • Cell Signaling Technology已认证
  • USA
  • 2025年11月11日
  • W, IF-IC
  • Rabbit
  • H
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    • 详细信息
    • 技术资料
    • 抗体英文名

      RAIG1 Antibody

    • 抗原

      synthetic peptide corresponding to residues surrounding Val295 of human RAIG1 protein

    • 应用范围

      W, IF-IC

    • 宿主

      Rabbit

    • 保质期

      详见说明书

    • 适应物种

      H

    • 库存

      大量

    • 级别

      详见MSDS文件

    • 供应商

      CST

    • 是否单克隆

      2

    • 保存条件

      -20°c

    • 规格

      100 ul (10 western blots)/carrier free & custom formulation / quantity

    规格:产品价格:¥请询价
    规格:100 ul (10 western blots)产品价格:¥请询价
    规格:carrier free & custom formulation / quantity产品价格:¥请询价

    pathway more info application references datasheet PDF MSDS PDF protocols

    Applications Key:  W=Western Blotting  IF-IC=Immunofluorescence (Immunocytochemistry)
    Reactivity Key:  H=Human
    Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on 100% sequence homology.

    Applications Reactivity Sensitivity MW (kDa) Source
    W IF-IC H Endogenous 40-50 Rabbit
    Protocols
    Specificity / Sensitivity

    RAIG1 Antibody recognizes endogenous levels of total RAIG1 protein.

    Source / Purification

    Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Val295 of human RAIG1 protein. Antibodies are purified by protein A and peptide affinity chromatography.

    Western Blotting

    Western Blotting

    Western blot analysis of extracts from untransfected or human RAIG1-transfected 293T cells and untransfected MKN-45 cells using RAIG1 Antibody.

    IF-IC

    IF-IC

    Confocal immunofluorescent analysis of MKN-45 (left) and 293 (right) cells using RAIG1 Antibody (green). Actin filaments have been labeled with DY-554 phalloidin. Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye).

    Background

    Retinoic Acid-Induced Gene 1 (RAIG1), also called RAI3 and GPRC5A, belongs to the family of G protein-coupled receptors (GPCRs). GPCRs are the largest and most abundant receptor family in mammals, composed of more than one thousand members (1). Retinoic Acids (RA) are a group of pleiotropic signaling molecules that regulate a broad range of physiologic and developmental processes. It is thought that RAIG1 may be a downstream target of RA signaling (2). RAIG1 is expressed in lung tissue and in several lung cancer cell lines, and encodes a seven-transmembrane glycoprotein presumed to be a lung tumor suppressor gene (3,4).

    1. Jörissen, H. et al. (2009) BMC Cancer 9, 200.
    2. Xu, J. et al. (2005) Am J Respir Cell Mol Biol 32, 381-7.
    3. Veling, G. et al. (1992) Kinderkrankenschwester 11, 118-20.
    4. Ye, X. et al. (2009) Cancer Biol Ther 8, 951-62.
    Application References

    Have you published research involving the use of our products? If so we'd love to hear about it. Please let us know !

    Companion Products

    Cell Signaling Technology® is a registered trademark of Cell Signaling Technology, Inc.


    For Research Use Only. Not For Use In Diagnostic Procedures.

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