Succinyl-CoA Synthetase Antibody

Succinyl-CoA Synthetase Antibo

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  • 询价
  • Cell Signaling Technology已认证
  • USA
  • 2025年11月01日
  • W, IP
  • Rabbit
  • H,M,R
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    • 详细信息
    • 技术资料
    • 抗体英文名

      Succinyl-CoA Synthetase Antibody

    • 抗原

      synthetic peptide corresponding to residues near the amino terminus of human succinyl-CoA synthetase (α subunit) protein

    • 应用范围

      W, IP

    • 宿主

      Rabbit

    • 保质期

      详见说明书

    • 适应物种

      H,M,R

    • 供应商

      CST

    • 级别

      详见MSDS文件

    • 库存

      大量

    • 是否单克隆

      2

    • 保存条件

      -20°c

    • 规格

      100 ul (10 western blots)/carrier free & custom formulation / quantity

    规格:产品价格:¥请询价
    规格:100 ul (10 western blots)产品价格:¥请询价
    规格:carrier free & custom formulation / quantity产品价格:¥请询价

    pathway more info application references datasheet PDF MSDS PDF protocols

    Applications Key:  W=Western Blotting  IP=Immunoprecipitation
    Reactivity Key:  H=Human  M=Mouse  R=Rat
    Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on 100% sequence homology.

    Applications Reactivity Sensitivity MW (kDa) Source
    W IP H M R Endogenous 36 Rabbit
    Protocols
    Specificity / Sensitivity

    Succinyl-CoA Synthetase Antibody detects endogenous levels of total succinyl-CoA synthetase (α subunit) protein.

    Source / Purification

    Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues near the amino terminus of human succinyl-CoA synthetase (α subunit) protein. Antibodies are purified by protein A and peptide affinity chromatography.

    Western Blotting

    Western Blotting

    Western blot analysis of extracts from various cell lines and tissue using Succinyl-CoA Synthetase Antibody.

    Background

    Succinyl-CoA synthetase α subunit (SUCLG1) catalyzes the conversion of succinate to succinyl-CoA and plays a key role in the citric acid cycle (1,2). Deficiency of this enzyme leads to a variety of diseases including fatal infantile lactic acidosis (3) and mitochondrial hepatoencephalomyopathy (4).

    1. Johnson, J.D. et al. (1998) J Biol Chem 273, 27580-6.
    2. Phillips, D. et al. (2009) Biochemistry 48, 7140-9.
    3. Ostergaard, E. et al. (2007) Am J Hum Genet 81, 383-7.
    4. Van Hove, J.L. et al. (2010) Pediatr Res 68, 159-64.
    Application References

    Have you published research involving the use of our products? If so we'd love to hear about it. Please let us know !

    Companion Products

    For Research Use Only. Not For Use In Diagnostic Procedures.

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