- 询价
- Cell Signaling Technology
- 5159
- USA
- 2025年07月15日
- W
- Rabbit
- H
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- 详细信息
- 技术资料
- 抗体英文名：
MYH Antibody
- 抗原：
synthetic peptide corresponding to carboxy terminal residues of human MYH protein
- 应用范围：
W
- 宿主：
Rabbit
- 适应物种：
H
- 级别：
详见MSDS文件
- 供应商：
CST
- 保质期：
详见说明书
- 库存：
大量
- 是否单克隆：
2
- 保存条件：
-20°c
- 规格：
100 ul (10 western blots)/carrier free & custom formulation / quantity
| 规格： | 产品价格： | ￥请询价 | |
|---|---|---|---|
| 规格： | 100 ul (10 western blots) | 产品价格： | ￥请询价 |
| 规格： | carrier free & custom formulation / quantity | 产品价格： | ￥请询价 |
pathway more info application references datasheet PDF MSDS PDF protocols
Applications Key: W=Western Blotting
Reactivity Key: H=Human
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on 100% sequence homology.
| Applications | Reactivity | Sensitivity | MW (kDa) | Source |
|---|---|---|---|---|
| W | H | Endogenous | 55 | Rabbit |
| Protocols |
|
|---|---|
| Specificity / Sensitivity | MYH Antibody detects endogenous levels of total MYH protein. Based on the amino acid sequence, the antibody is expected to react with all isoforms of human MYH protein. |
| Source / Purification | Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to carboxy terminal residues of human MYH protein. Antibodies are purified using protein A and peptide affinity chromatography. Western Blotting
Western blot analysis of extracts from various cell types using MYH Antibody. Western Blotting
Western blot analysis of extracts from COS-7 cells, mock transfected (-) or MYH-transfected (+), using MYH Antibody. |
| Background | Base excision repair (BER) proteins catalyze the removal of incorrect or damaged bases, including oxidized bases, from DNA. N-glycosylases specific to a given lesion remove the incorrect base as the first step in BER. MYH is the mammalian ortholog of E. coli MutY, a DNA glycosylase that catalyzes the removal of 8-oxoG:A mismatches (1). Several MYH isoforms have been detected in human cells localizing to either the nucleus or the mitochondria (2). MYH interacts with DNA repair proteins and localizes to DNA damage foci after oxidative damage (3). Mutations in the corresponding MYH gene are associated with human gastric (4) and colorectal (5-7) cancers.
|
| Application References | Have you published research involving the use of our products? If so we'd love to hear about it. Please let us know ! |
| Companion Products |
For Research Use Only. Not For Use In Diagnostic Procedures. |
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