Dexras1 Antibody

Dexras1 Antibody

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  • 询价
  • Cell Signaling Technology已认证
  • USA
  • 2025年12月10日
  • W
  • Rabbit
  • H
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    • 详细信息
    • 技术资料
    • 抗体英文名

      Dexras1 Antibody

    • 抗原

      synthetic peptide corresponding to residues near the carboxy terminus of human Dexras1 protein

    • 应用范围

      W

    • 宿主

      Rabbit

    • 保质期

      详见说明书

    • 适应物种

      H

    • 供应商

      CST

    • 库存

      大量

    • 级别

      详见MSDS文件

    • 是否单克隆

      2

    • 保存条件

      -20°c

    • 规格

      100 ul (10 western blots)/carrier free & custom formulation / quantity

    规格:产品价格:¥请询价
    规格:100 ul (10 western blots)产品价格:¥请询价
    规格:carrier free & custom formulation / quantity产品价格:¥请询价

    pathway more info application references datasheet PDF MSDS PDF protocols

    Applications Key:  W=Western Blotting
    Reactivity Key:  H=Human
    Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on 100% sequence homology.

    Applications Reactivity Sensitivity MW (kDa) Source
    W H Endogenous 30 Rabbit
    Protocols
    Specificity / Sensitivity

    Dexras1 Antibody detects endogenous levels of total Dexras1 protein. The antibody also cross-reacts with a 60 kDa protein of unknown origin.

    Source / Purification

    Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human Dexras1 protein. Antibodies were purified by protein A and peptide affinity chromatography.

    Western Blotting

    Western Blotting

    Western blot analysis of extracts from HeLa and Hep G2 cells using Dexras1 Antibody.

    Background

    Dexras1 (Ras dexamethasone induced 1) belongs to the Ras superfamily of GTPases and was initially identified as a dexamethasone inducible gene (1,2). Dexras1 reportedly regulates several distinct signal transduction pathways, including MAPK signaling, NMDA receptor-nitric oxide-mediated signaling, and pathways involving adenylyl cyclases (3-5). Dexras1 can directly modulate FE65-APP-mediated transcription and regulate the photic sensitivity of the mammalian circadian clock (6,7).

    1. Kemppainen, R.J. and Behrend, E.N. (1998) J Biol Chem 273, 3129-31.
    2. Tu, Y. and Wu, C. (1999) Biochim Biophys Acta 1489, 452-6.
    3. Fang, M. et al. (2000) Neuron 28, 183-93.
    4. Graham, T.E. et al. (2004) Biochem Biophys Res Commun 316, 307-12.
    5. Nguyen, C.H. and Watts, V.J. (2005) Biochem Biophys Res Commun 332, 913-20.
    6. Cheng, H.Y. et al. (2006) J Neurosci 26, 12984-95.
    7. Lau, K.F. et al. (2008) J Biol Chem 283, 34728-37.
    Application References

    Have you published research involving the use of our products? If so we'd love to hear about it. Please let us know !

    Companion Products

    For Research Use Only. Not For Use In Diagnostic Procedures.

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