- 询价
- Cell Signaling Technology
- 13609S
- USA
- 2026年07月12日
- W IP
- Rabbit
- H Mk
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- 详细信息
- 文献和实验
- 技术资料
- 靶点：
POLG
- 应用范围：
W IP
- 宿主：
Rabbit
- 适应物种：
H Mk
- 克隆性：
单克隆
- 保存条件：
-20℃
- 规格：
100µl
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文献和实验Functional Analysis of Mutant Mitochondrial DNA Polymerase Proteins Involved in Human Disease
DNA polymerase γ (pol γ) is the only DNA polymerase within the mitochondrion and is thus essential for replication and repair of mtDNA. POLG , the gene encoding the catalytic subunit of pol γ, is a major locus for a wide spectrum
involving nuclear-encoded proteins that are required at the mitochondrial DNA replication fork, which often leads to human disorders and to animal lethality during development. DNA polymerase γ (pol γ), the mitochondrial replicase, and the mitochondrial
assay that differentiates the mitochondrial form from what generally prove to be multiple, and much more abundant, nuclear counterparts. A case in point is the mitochondrial DNA polymerase, pol γ. Pol γ was the third DNA polymerase identified in animal
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