Concentration: 1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background: The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
糖原合酶激酶-3β抗体 Specificity: ● Mouse Polyclonal IgG, affinity purified by Protein A.
● Reacts with: Human, Mouse, Rat, Chicken, Dog, Cow, Sheep, .
● Immunogen: KLH conjugated synthetic peptide derived from human GSK-3 Beta.
● Predicted Molecular Weight: 47kDa.
Storage: Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles). Application: WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
激酶和磷酸酶(Kinases and Phosphatases)
GSK-3β是一个serine/threonine,proline 直接激酶,参与多个信号通路的排列,包括糖原合成和细胞黏附,GSK3β与AD病有关。此抗体识别分子量为47kDa 的GSK-3β蛋白