Stemgent™ Purified Rabbit anti-Mouse/Human Sox2 Antibody was screened on human and mouse embryonic stem (ES) cells using immunocytochemistry (ICC) and intracellular staining by flow cytometry (FC) and selected as the best Sox2 antibody available for researchers needing to demonstrate pluripotency. Sox2, also known as SRY (sex determining region Y)-box 2, is a transcription factor essential for maintaining self-renewal of undifferentiated ES cells and is one of the key transcription factors used to reprogram mouse and human fibroblasts to a pluripotent state1-3.