FRA2/FOSL2抗体

FRA2/FOSL2抗体产品类别

兔抗人、大、小鼠FRA-2/FOSL2蛋白抗体

产品价格

0.1ml/480元 0.2ml/650元

产品标准

浓缩液(1mg/1ml) 亲和纯化抗体

产品应用

WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 （石蜡切片需做抗原修复）

FRA2/FOSL2抗体产品介绍

FOSL2蛋白对细胞因子、生长因子、感染或致癌刺激等生理或病理信号发生应答,调节基因的转录, 参与细胞的增殖、分化等过程. FOSL2在肿瘤形成及发展过程中, 通过促进细胞增殖、抑制分化、促进肿瘤细胞的侵袭和转移等过程发挥作用.
Fos and Jun dimerize to form Activator Protein 1 (AP1), a transcriptional factor that binds to the 12-O-tetradecanoylphorbol 13 acetate (TPA) response element (TRE) of several cellular and viral genes including human collagenase, metallothionein IIa, stromelysin, interleukin 2, SV40 and polyoma. Fos and Jun contain the 'leucine-zipper' motif that allows for dimerization and an adjacent basic domain required for biological activity. The functionally active form of Fos is in a heterodimer with a member of the Jun family. While Jun family members can form functional homodimers, studies indicate that Fos family members do not self-associate and therefore do not bind DNA on their own. The various dimers differ in their ability to transactivate AP1 dependent genes.
mol wt:36kDa
Other Aliases:
FLJ23306; Fos L2; FOS like antigen 2; Fos related antigen 2; FosL 2; FosL2; FRA 2xy-0239R HIV gp41艾滋病病毒抗体
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xy-2915R HOXD10同源盒蛋白HOXD10抗体
xy-15476R HHIPL1 HHIP样蛋白1抗体
xy-2502R HOXA10HOXA10抗体
xy-0984R hCG receptor 促黄体生成素受体抗体
xy-2156R HER2 receptor(NT)HER2受体抗体(N端)
xy-2155R HER2 receptor(NT)HER2受体抗体
xy-10301R H7N9 HAA型禽流感病毒H7N9 M1蛋白抗体
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xy-1541R Heparanase 1乙酰肝素酶抗体
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xy-15478R HHLA1HHLA1蛋白抗体
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xy-4626R HE4附睾分泌蛋白4抗体
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xy-15491R HIGD2AHIG1区域家族成员2A抗体
xy-1808R Hpt/Haptoglobin结合珠蛋白/触珠蛋白抗体
xy-1820R HMGB4高迁移率族蛋白B4抗体
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xy-1775R HFH-4叉头蛋白J1抗体
xy-4981R HIV p55+NP7艾滋病病毒抗体
xy-4980R HIV p55+P6-Gag艾滋病病毒抗体
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xy-9912R HPR结合珠蛋白相关蛋白抗体
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FRA2/FOSL2抗体