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- 2025年07月07日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
4℃保存
- 保质期：
6个月
- 英文名：
Stemolecule BIX01294
- 库存：
1
- 供应商：
上海信裕
- Stemolecule BIX01294保存于运输说明：
- 4°C protected from light. Following reconstitution, store aliquots at -20°C
- 详细信息：
-
Stemolecule™ BIX01294
甲基转移酶(G
BIX01294 is a selective inhibitor of G9a histone methyl transferase (G9a HMTase) that impairs G9a HMTase and generation of H3K9me2 in vitro1. G9a HMTase regulates gene expression including one of the pluripotency genes Oct42. Shi and colleagues (2008) found that BIX01294 enhances reprogramming efficiency of neural progenitor cells to the same levels as when four transcription factors (Oct4, Klf4, Sox2 and c-Myc) were introduced to somatic cells for generation of induced pluripotent stem cells2. View Poster
Stemolecule BIX01294产品参数
Chemical Formula C28H38N6O2 Structure Molecular Weight 490.64 CAS Number 935693-62-2 Purity >94.9% by HPLC analysis Formulation Pale yellow solid Solubility Soluble in DMSO (100 mM). For a 10 mM concentrated stock solution, reconstitute the compound by adding 1019 µl of DMSO to the entire contents of the vial. Note: for most cells, the maximum tolerance to DMSO is <0.5%. Storage 4°C protected from light. Following reconstitution, store aliquots at -20°C Stability Stock solutions stable at -20°C for 6 months Quality Control Stemolecule BIX01294 The purity of BIX01294 was determined by HPLC analysis. The accurate mass and structure of BIX01294 was determined by mass spectrometry and NMR, respectively. Cellular toxicity of BIX01294 was tested by using HeLa and HEK293 cells. References - Kubicek, S. et al., Mol. Cell. 3rd ed., 25:473-481 (2007)
- 2. Shi, Y. et al., Cell Stem Cell, 2:525-528 (2008).
MSDS
Wiki
Stemolecule BIX01294
xy-0082xy CASP4(Caspase-4)半胱胺酸蛋白酶蛋白-4抗原
xy-0175xy Trk B神经生长因子受体的一种（抗原）
xy-2227xy GDF8/MSTN(growth differntiation factor 8)重组生长分化因子8/肌肉抑制素
xy-0288xy Trk B神经生长因子受体的一种（抗原）
xy-0176xy Trk C神经生长因子受体的一种（抗原）
xy-0003xy TSHR (Thyroid stimulating hormone receptor)(NT)促甲状腺素受体（抗原）
xy-0052xy Caspase-8 (pro Mch5)半胱氨酸蛋白酶8抗原
xy-0206xy TSHR (Thyroid stimulating hormone receptor)(CT)促甲状腺素受体（抗原）
xy-0016xy TY3H ( Tyrosine Hydroxylase )酪氨酸羟化酶（抗原）
xy-0159xy Tubulin-Alpha微管蛋白（抗原）
xy-1453xy Cav-1/ETM1 peptide细胞质膜微囊蛋白-1抗原
xy-1165xy Beta-catenin/ Beta-cats β-连环蛋白抗原（β-β链接素）
xy-2063xy p- Beta catenin(p-beta Catenin(phosphor-Y142))磷酸化β-连环蛋白抗原
xy-0210xy Tubulin- Beta微管蛋白（抗原）
xy-0452xy NAIF1 protein( CB12-327)核凋亡诱导因子蛋白1(多肽)
xy-1500xy cath-B/CB(Cathepsin B)组织蛋白酶B抗原
xy-1508xy cath-L/CL peptide组织蛋白酶L抗原
xy-1134xy CBFA1/RUNX2 (Runt-related Transcription Factor 2)成骨特异性转录因子（多肽）
xy-1397xy CBP(CREB-binding protein)CREB结合蛋白抗原
xy-1421xy CBX3/HP1 gamma染色盒同源物3抗原
xy-0955xy CBX5(Chromobox Homolog 5)CBX5（多肽）
xy-1487xy CC16(Clara cell protein 16) peptide克拉拉细胞蛋白(Clara细胞分泌蛋白)抗原
xy-0562xy CCR-2/5(CC chemokine receptor 2/5)CC趋化因子受体2/5抗原
xy-2450xy CCL1/TCA3/I-309嗜酸粒细胞趋化蛋白CCL1抗原
xy-1324xy CCL5/RANTES(regulated on activation normal T cell expressed and secreted)活化T细胞表达和分泌的调节因子抗原
xy-2475xy CCL4/MIP-1 Beta(Macrophage Inflammatory Protein 1 beta)巨噬细胞炎性蛋白1β抗原
xy-1268xy MIP3 Alpha/CCL20(Macrophage inflammatory ptotein 3 alpha)巨噬细胞炎性蛋白3α抗原
xy-2478xy CCL12/MCP-5(C-C motif chemokine 12)单核细胞趋化蛋白5抗原
xy-2479xy CCL14/HCC-1(C-C motif chemokine 14)嗜酸粒细胞趋化蛋白14抗原
xy-1761xy ABCD-1/CCL22嗜酸粒细胞趋化蛋白22抗原
xy-2454xy MIP-3 beta/ELC/CCL19(Macrophage Inflammatory Protein 3 Beta)巨噬细胞炎性蛋白19抗原
xy-1762xy CCL26(Eotaxin 3)嗜酸粒细胞趋化蛋白3抗原
xy-1169xy CCR-1(CC chemokine receptor 1)细胞表面趋化因子受体1抗原
xy-1167xy CCR-3(CC chemokine receptor 3)CC趋化因子受体3抗原
xy-1671xy CCR-2A(C-C Chemokine receptor 2A)细胞表面趋化因子受体2A抗原
xy-1168xy CCR-4(C-C chemokine receptor 4)细胞表面趋化因子受体4抗原
xy-1542xy CCR-6/CD196 peptide细胞表面趋化因子受体6抗原
Stemolecule BIX01294xy-1628xy CXCR6(CXC-chemokine receptor 6) peptide细胞表面趋化因子受体6抗原
xy-1305xy CCR-7(CC chemokine receptor 7)CC趋化因子受体7（多肽）
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文献和实验Using RepeatMasker to Identify Repetitive Elements in Genomic Sequences
RECON Web site http://bix.ucsd.edu/repeatscout/
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