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- 保质期：
6个月
- 英文名：
Sphingosine 1 Phosphate Assay Services
- 库存：
1
- 供应商：
上海信裕
Sphingosine 1 Phosphate Assay Services Description:
Measurement of bioactive lipids using immunoassays and receptor interaction methodologies
Sphingosine 1 Phosphate (S1P) is a key component of the sphingolipid signaling cascade. S1P initiates a proliferative, pro-angiogenic, and anti-apoptotic sequence of events contributing to cancer progression. Recent research has suggested that S1P is a potent tumorigenic growth factor that is likely released from tumor cells and that S1P may be a novel biomarker for early stage cancer detection. Sphingosine kinase has also been shown to be up-regulated in a variety of cancer types (S1P is produced via the activity of sphingosine kinase phosphorylating sphingosine). The Echelon S1P Assay is a sensitive and robust method for the quantification of S1P in biological samples.
Sphingosine 1 Phosphate Assay Services
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文献和实验Quantifying Sphingosine-1-Phosphate-Dependent Activation of the RhoGTPases
The GPCR-coupled sphingosine-1-phosphate (S1P) receptors regulate a number of important cell �functions, including proliferation, migration, and adhesion. Since these processes require dynamic regulation of the actin cytoskeleton, the ability
Utilizing Sphingosine-1-Phosphate to Stimulate Sprouting Angiogenesis
into the surrounding matrix, and form sprouting structures connecting neighboring vessels. Sphingosine-1-phosphate (S1P), a biologically active sphingolipid, promotes vessel morphogenesis and angiogenesis during embryonic development and in adults under normal
Sphingosine Kinase: Assay and Product Analysis
fraction of certain tissues and organisms (8 ,9 ). The reaction product, sphingosine-1-phosphate (SPP), was considered for more than 20 yr to be merely an intermediate in the catabolism of long-chain sphingoid bases to palmitaldehyde
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